BTSR_SALTY
ID BTSR_SALTY Reviewed; 239 AA.
AC Q8ZNN2;
DT 23-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Transcriptional regulatory protein BtsR {ECO:0000250|UniProtKB:P0AFT5};
GN Name=btsR {ECO:0000250|UniProtKB:P0AFT5}; Synonyms=yehT;
GN OrderedLocusNames=STM2158;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Member of the two-component regulatory system BtsS/BtsR. BtsR
CC regulates expression of btsT by binding to its promoter region.
CC {ECO:0000250|UniProtKB:P0AFT5}.
CC -!- PTM: Phosphorylated by BtsS. {ECO:0000250|UniProtKB:P0AFT5}.
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DR EMBL; AE006468; AAL21062.1; -; Genomic_DNA.
DR RefSeq; NP_461103.1; NC_003197.2.
DR RefSeq; WP_000598637.1; NC_003197.2.
DR AlphaFoldDB; Q8ZNN2; -.
DR SMR; Q8ZNN2; -.
DR STRING; 99287.STM2158; -.
DR PaxDb; Q8ZNN2; -.
DR EnsemblBacteria; AAL21062; AAL21062; STM2158.
DR GeneID; 1253680; -.
DR KEGG; stm:STM2158; -.
DR PATRIC; fig|99287.12.peg.2284; -.
DR HOGENOM; CLU_000445_14_1_6; -.
DR OMA; IQAFEEH; -.
DR PhylomeDB; Q8ZNN2; -.
DR BioCyc; SENT99287:STM2158-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0032993; C:protein-DNA complex; IBA:GO_Central.
DR GO; GO:0001216; F:DNA-binding transcription activator activity; IBA:GO_Central.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR007492; LytTR_DNA-bd_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR039420; WalR-like.
DR PANTHER; PTHR48111; PTHR48111; 1.
DR Pfam; PF04397; LytTR; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00850; LytTR; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS50930; HTH_LYTTR; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW DNA-binding; Phosphoprotein; Reference proteome; Transcription;
KW Transcription regulation; Two-component regulatory system.
FT CHAIN 1..239
FT /note="Transcriptional regulatory protein BtsR"
FT /id="PRO_0000081365"
FT DOMAIN 3..116
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT DOMAIN 137..239
FT /note="HTH LytTR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00112"
FT MOD_RES 54
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 239 AA; 27410 MW; 0DF400BDB2EE4DB3 CRC64;
MIKVLIVDDE PLARENLRIL LQGQDDIEIV GECANAVEAI GAVHKLRPDV LFLDIQMPRI
SGLEMVGMLD PEHRPYIVFL TAFDEYAIKA FEEHAFDYLL KPIEEKRLEK TLHRLRQERS
KQDVSLLPEN QQALKFIPCT GHSRIYLLQM DDVAFVSSRM SGVYVTSSEG KEGFTELTLR
TLESRTPLLR CHRQFLVNMA HLQEIRLEDN GQAELILRNG LTVPVSRRYL KSLKEAIGL
