TORI_ECOUT
ID TORI_ECOUT Reviewed; 66 AA.
AC Q1R904;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 1.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=Response regulator inhibitor for tor operon;
DE Short=Tor inhibitor;
GN Name=torI; OrderedLocusNames=UTI89_C2694;
OS Escherichia coli (strain UTI89 / UPEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=364106;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UTI89 / UPEC;
RX PubMed=16585510; DOI=10.1073/pnas.0600938103;
RA Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A.,
RA Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S.,
RA Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J.,
RA Gordon J.I.;
RT "Identification of genes subject to positive selection in uropathogenic
RT strains of Escherichia coli: a comparative genomics approach.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006).
CC -!- FUNCTION: Transcription inhibitory protein for the torCAD operon. Also
CC acts as an excisionase and plays an essential role in the defective
CC prophage CPS53 excision (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with TorR. Binds to the effector domain of TorR.
CC This interaction, which does not interfere with TorR DNA binding
CC activity, probably prevents the recruitment of RNA polymerase to the
CC torCAD promoter. Binds to DNA (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the phage AlpA excisionase family.
CC {ECO:0000305}.
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DR EMBL; CP000243; ABE08160.1; -; Genomic_DNA.
DR RefSeq; WP_001163428.1; NC_007946.1.
DR AlphaFoldDB; Q1R904; -.
DR BMRB; Q1R904; -.
DR SMR; Q1R904; -.
DR EnsemblBacteria; ABE08160; ABE08160; UTI89_C2694.
DR GeneID; 60669294; -.
DR KEGG; eci:UTI89_C2694; -.
DR HOGENOM; CLU_140176_22_2_6; -.
DR OMA; CAFKSKL; -.
DR Proteomes; UP000001952; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW DNA recombination; DNA-binding; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..66
FT /note="Response regulator inhibitor for tor operon"
FT /id="PRO_0000252163"
SQ SEQUENCE 66 AA; 7678 MW; 587B519EF433DC5B CRC64;
MQHELQPDSL VDLKFIMADT GFGKTFIYDR IKSGDLPKAK VIHGRARWLY RDHCEFKNKL
LSRANG