ID   TOTX_DROSE              Reviewed;         150 AA.
AC   B4II52;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 38.
DE   RecName: Full=Protein Turandot X1/X2;
DE   Flags: Precursor;
GN   Name=TotX1 {ECO:0000250|UniProtKB:Q8IN41}; ORFNames=GM15120;
GN   and
GN   Name=TotX2 {ECO:0000250|UniProtKB:Q8IN41}; ORFNames=GM23148;
OS   Drosophila sechellia (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7238;
RN   [1] {ECO:0000312|EMBL:EDW49596.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (GM15120 AND GM23148).
RC   STRAIN=Rob3c / Tucson 14021-0248.25 {ECO:0000312|EMBL:EDW49596.1};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: A humoral factor that may play a role in stress tolerance.
CC       {ECO:0000250|UniProtKB:Q8IN41}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q8IN41}.
CC   -!- SIMILARITY: Belongs to the Turandot family. {ECO:0000255}.
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DR   EMBL; CH480842; EDW49596.1; -; Genomic_DNA.
DR   EMBL; CH480853; EDW51640.1; -; Genomic_DNA.
DR   RefSeq; XP_002043412.1; XM_002043376.1.
DR   RefSeq; XP_002044296.1; XM_002044260.1.
DR   AlphaFoldDB; B4II52; -.
DR   EnsemblMetazoa; FBtr0198105; FBpp0196597; FBgn0170040.
DR   EnsemblMetazoa; FBtr0206133; FBpp0204625; FBgn0178016.
DR   GeneID; 6619300; -.
DR   KEGG; dse:6619300; -.
DR   HOGENOM; CLU_1817777_0_0_1; -.
DR   OMA; QFERFIH; -.
DR   PhylomeDB; B4II52; -.
DR   Proteomes; UP000001292; Unassembled WGS sequence.
DR   GO; GO:0005615; C:extracellular space; ISS:UniProtKB.
DR   GO; GO:0034605; P:cellular response to heat; IEA:UniProt.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0009617; P:response to bacterium; ISS:UniProtKB.
DR   GO; GO:0009408; P:response to heat; ISS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
DR   InterPro; IPR010825; Turandot.
DR   Pfam; PF07240; Turandot; 1.
PE   3: Inferred from homology;
KW   Immunity; Innate immunity; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..150
FT                   /note="Protein Turandot X1/X2"
FT                   /id="PRO_0000355003"
FT   REGION          127..150
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        133..150
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   150 AA;  17265 MW;  6F09F99996367F07 CRC64;
     MRLYIGSLLI CVLLGIVPFA TANTNRSGYE EHRNYLLNIF HNPLVNDSIK EKNIPELIAF
     YQRYPTDIPL SDADRQQFER FIHDYREYRE VLVDGVPPQG GSFGNIFGHF LGRVGTRYIS
     SLFNKKREEG QSNHANSPTT SPSRIQKMTK