ID   TOTX_DROSI              Reviewed;         150 AA.
AC   B4R1P9;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 43.
DE   RecName: Full=Protein Turandot X;
DE   Flags: Precursor;
GN   Name=TotX {ECO:0000250|UniProtKB:Q8IN41}; ORFNames=GD20023;
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240;
RN   [1] {ECO:0000312|EMBL:EDX12158.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: A humoral factor that may play a role in stress tolerance.
CC       {ECO:0000250|UniProtKB:Q8IN41}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q8IN41}.
CC   -!- SIMILARITY: Belongs to the Turandot family. {ECO:0000255}.
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DR   EMBL; CM000364; EDX12158.1; -; Genomic_DNA.
DR   RefSeq; XP_002102655.1; XM_002102619.2.
DR   AlphaFoldDB; B4R1P9; -.
DR   EnsemblMetazoa; FBtr0219933; FBpp0218425; FBgn0191505.
DR   GeneID; 6727263; -.
DR   HOGENOM; CLU_1817777_0_0_1; -.
DR   OMA; QFERFIH; -.
DR   PhylomeDB; B4R1P9; -.
DR   Proteomes; UP000000304; Chromosome 3r.
DR   Bgee; FBgn0191505; Expressed in adult organism and 2 other tissues.
DR   GO; GO:0005615; C:extracellular space; ISS:UniProtKB.
DR   GO; GO:0034605; P:cellular response to heat; IEA:EnsemblMetazoa.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:EnsemblMetazoa.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0009617; P:response to bacterium; ISS:UniProtKB.
DR   GO; GO:0009408; P:response to heat; ISS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
DR   InterPro; IPR010825; Turandot.
DR   Pfam; PF07240; Turandot; 1.
PE   3: Inferred from homology;
KW   Immunity; Innate immunity; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..150
FT                   /note="Protein Turandot X"
FT                   /id="PRO_0000355004"
FT   REGION          127..150
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        133..150
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   150 AA;  17190 MW;  73659ABB44C58329 CRC64;
     MGLHIGSLLI CVFLGILPFA TANTNRSGYE EQRNYLLNIF HNPLVNDSIK EKNIPELIAF
     YQRYPTDVPL SDADRQQFER FIHDYREYRE VLVDGVPPQG GSFGNIFGHF LGRVGTRYIS
     SLFNKKREEG QSNHANSPTT LPSRIQKMTK