ID   TOTZ_DROPS              Reviewed;         151 AA.
AC   Q299E7;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Protein Turandot Z;
DE   Flags: Precursor;
GN   Name=TotZ {ECO:0000312|EMBL:EAL27756.1}; ORFNames=GA16287;
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245;
RN   [1] {ECO:0000312|EMBL:EAL27756.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94;
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA   Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA   Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA   Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA   Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA   Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA   Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT   gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
CC   -!- FUNCTION: A humoral factor that may play a role in stress tolerance.
CC       {ECO:0000250|UniProtKB:Q8IN41}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q8IN41}.
CC   -!- SIMILARITY: Belongs to the Turandot family. {ECO:0000255}.
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DR   EMBL; CM000070; EAL27756.1; -; Genomic_DNA.
DR   RefSeq; XP_001358615.1; XM_001358578.2.
DR   AlphaFoldDB; Q299E7; -.
DR   SMR; Q299E7; -.
DR   EnsemblMetazoa; FBtr0285421; FBpp0283859; FBgn0076303.
DR   GeneID; 4801541; -.
DR   KEGG; dpo:Dpse_GA16287; -.
DR   HOGENOM; CLU_1733395_0_0_1; -.
DR   InParanoid; Q299E7; -.
DR   OMA; PIQGGVW; -.
DR   PhylomeDB; Q299E7; -.
DR   Proteomes; UP000001819; Chromosome 2.
DR   Bgee; FBgn0076303; Expressed in insect adult head.
DR   GO; GO:0005615; C:extracellular space; ISS:UniProtKB.
DR   GO; GO:0034605; P:cellular response to heat; IEA:UniProt.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0009617; P:response to bacterium; IEA:UniProt.
DR   GO; GO:0009408; P:response to heat; ISS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
DR   GO; GO:0009411; P:response to UV; ISS:UniProtKB.
DR   InterPro; IPR010825; Turandot.
DR   Pfam; PF07240; Turandot; 1.
PE   3: Inferred from homology;
KW   Immunity; Innate immunity; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..151
FT                   /note="Protein Turandot Z"
FT                   /id="PRO_0000355008"
SQ   SEQUENCE   151 AA;  16881 MW;  31D8CCF856EA47A5 CRC64;
     MSRLIHLSFV LALLACLTGP ISANPIDDDR ERLNQLLSNP EPADDAELLR NTQEAIALYK
     KHASRTLPGH QVELDLDRDI RAFETEHLTV DGLPIQGGVW DLIKRGADKV PDEVKDQAKE
     LAKTTAKVLF NKLTEYLKKK ISGEDAEKKD T