ID   TOTZ_DROSI              Reviewed;         148 AA.
AC   B4R1Q1;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Protein Turandot Z;
DE   Flags: Precursor;
GN   Name=TotZ {ECO:0000312|EMBL:EDX12160.1}; ORFNames=GD19385;
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240;
RN   [1] {ECO:0000312|EMBL:EDX12160.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: A humoral factor that may play a role in stress tolerance.
CC       {ECO:0000250|UniProtKB:Q8IN41}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q8IN41}.
CC   -!- SIMILARITY: Belongs to the Turandot family. {ECO:0000255}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM000364; EDX12160.1; -; Genomic_DNA.
DR   RefSeq; XP_002102657.1; XM_002102621.2.
DR   AlphaFoldDB; B4R1Q1; -.
DR   EnsemblMetazoa; FBtr0219295; FBpp0217787; FBgn0190886.
DR   GeneID; 6727268; -.
DR   HOGENOM; CLU_1760725_0_0_1; -.
DR   OMA; FKRKTMV; -.
DR   PhylomeDB; B4R1Q1; -.
DR   Proteomes; UP000000304; Chromosome 3r.
DR   GO; GO:0005615; C:extracellular space; ISS:UniProtKB.
DR   GO; GO:0034605; P:cellular response to heat; IEA:EnsemblMetazoa.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:EnsemblMetazoa.
DR   GO; GO:0034644; P:cellular response to UV; IEA:EnsemblMetazoa.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0009617; P:response to bacterium; IEA:EnsemblMetazoa.
DR   GO; GO:0009408; P:response to heat; ISS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
DR   GO; GO:0009411; P:response to UV; ISS:UniProtKB.
DR   InterPro; IPR010825; Turandot.
DR   Pfam; PF07240; Turandot; 1.
PE   3: Inferred from homology;
KW   Immunity; Innate immunity; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..148
FT                   /note="Protein Turandot Z"
FT                   /id="PRO_0000355010"
SQ   SEQUENCE   148 AA;  16341 MW;  C9A23A9E3DA09C07 CRC64;
     MYFAIRLSFV LAVLFCLTGN GSARMLDADR NRLQQLQIRS QQSADANTQV DIAYEVIGIY
     DKYKGQGGSN VLREAQLNSQ VNDFKRKTMV IDGVPAQGGV WGILGAIKKA ADAVPDNVKK
     DAENLVKSST KVLVRGIYDY LMGKMKQH