ID   TP1A_RANBO              Reviewed;          13 AA.
AC   P84116;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   17-JUN-2020, entry version 32.
DE   RecName: Full=Temporin-1BYa;
OS   Rana boylii (Foothill yellow-legged frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana; Rana.
OX   NCBI_TaxID=160499;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, AMIDATION AT LEU-13, AND MASS SPECTROMETRY.
RC   TISSUE=Skin secretion {ECO:0000269|PubMed:14531844};
RX   PubMed=14531844; DOI=10.1034/j.1399-3011.2003.00090.x;
RA   Conlon J.M., Sonnevend A., Patel M., Davidson C., Nielsen P.F., Pal T.,
RA   Rollins-Smith L.A.;
RT   "Isolation of peptides of the brevinin-1 family with potent candidacidal
RT   activity from the skin secretions of the frog Rana boylii.";
RL   J. Pept. Res. 62:207-213(2003).
CC   -!- FUNCTION: Antibacterial activity against Gram-positive bacterium
CC       S.aureus. {ECO:0000269|PubMed:14531844}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:14531844}.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands.
CC   -!- MASS SPECTROMETRY: Mass=1381.9; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:14531844};
CC   -!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
CC       Temporin subfamily. {ECO:0000269|PubMed:14531844}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Amphibian defense peptide; Antibiotic; Antimicrobial;
KW   Direct protein sequencing; Secreted.
FT   PEPTIDE         1..13
FT                   /note="Temporin-1BYa"
FT                   /id="PRO_0000043569"
FT   MOD_RES         13
FT                   /note="Leucine amide"
FT                   /evidence="ECO:0000269|PubMed:14531844"
FT   UNSURE          13
FT                   /note="L or I"
FT                   /evidence="ECO:0000269|PubMed:14531844"
SQ   SEQUENCE   13 AA;  1384 MW;  C850402B9DECC33D CRC64;
     FLPIIAKVLS GLL