ID   TP1_ODOVE               Reviewed;          62 AA.
AC   Q1JS91;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-JUN-2006, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Temporin-1V;
DE            Short=temp1v;
DE   AltName: Full=1VE;
DE   Flags: Precursor;
OS   Odorrana versabilis (Chinese bamboo leaf odorous frog) (Rana versabilis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Odorrana.
OX   NCBI_TaxID=326940;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AMIDATION AT ILE-60, AND MASS SPECTROMETRY.
RC   TISSUE=Skin secretion;
RX   PubMed=16621152; DOI=10.1016/j.peptides.2006.02.009;
RA   Chen T., Zhou M., Rao P., Walker B., Shaw C.;
RT   "The Chinese bamboo leaf odorous frog (Rana (odorrana) versabilis) and
RT   north american rana frogs share the same families of skin antimicrobial
RT   peptides.";
RL   Peptides 27:1738-1744(2006).
CC   -!- FUNCTION: Antimicrobial peptide. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands.
CC   -!- MASS SPECTROMETRY: Mass=1370.03; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:16621152};
CC   -!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
CC       Temporin subfamily. {ECO:0000305}.
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DR   EMBL; AM113510; CAJ34606.1; -; mRNA.
DR   AlphaFoldDB; Q1JS91; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   InterPro; IPR004275; Frog_antimicrobial_propeptide.
DR   Pfam; PF03032; FSAP_sig_propep; 1.
PE   1: Evidence at protein level;
KW   Amidation; Amphibian defense peptide; Antibiotic; Antimicrobial;
KW   Cleavage on pair of basic residues; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   PROPEP          23..45
FT                   /id="PRO_0000268219"
FT   PEPTIDE         48..60
FT                   /note="Temporin-1V"
FT                   /id="PRO_0000268220"
FT   MOD_RES         60
FT                   /note="Isoleucine amide"
FT                   /evidence="ECO:0000269|PubMed:16621152"
SQ   SEQUENCE   62 AA;  7155 MW;  F5420E3928F9E346 CRC64;
     MFTLKKSLLL LFFLGTINLS LCEEERDADE EERRDDPDEM NVEVEKRFLP LVGKILSGLI
     GK