ID   TP8L1_DANRE             Reviewed;         186 AA.
AC   Q7SZE8;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Tumor necrosis factor alpha-induced protein 8-like protein 1;
DE            Short=TIPE1 {ECO:0000250|UniProtKB:Q8K288};
DE            Short=TNF alpha-induced protein 8-like protein 1;
DE            Short=TNFAIP8-like protein 1;
GN   Name=tnfaip8l1; Synonyms=tnfaip8; ORFNames=si:dkey-49m19.6, zgc:55331;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AB;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8K288}.
CC   -!- SIMILARITY: Belongs to the TNFAIP8 family. {ECO:0000305}.
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DR   EMBL; BX649252; CAK11082.1; -; Genomic_DNA.
DR   EMBL; BC052765; AAH52765.1; -; mRNA.
DR   RefSeq; NP_956626.1; NM_200332.1.
DR   AlphaFoldDB; Q7SZE8; -.
DR   SMR; Q7SZE8; -.
DR   STRING; 7955.ENSDARP00000119527; -.
DR   PaxDb; Q7SZE8; -.
DR   Ensembl; ENSDART00000124889; ENSDARP00000108146; ENSDARG00000086457.
DR   Ensembl; ENSDART00000140313; ENSDARP00000119527; ENSDARG00000086457.
DR   GeneID; 393303; -.
DR   KEGG; dre:393303; -.
DR   CTD; 126282; -.
DR   ZFIN; ZDB-GENE-040426-695; tnfaip8l1.
DR   eggNOG; ENOG502S00N; Eukaryota.
DR   GeneTree; ENSGT00390000003488; -.
DR   HOGENOM; CLU_085918_1_0_1; -.
DR   InParanoid; Q7SZE8; -.
DR   OMA; HQAVNTH; -.
DR   OrthoDB; 1284744at2759; -.
DR   PhylomeDB; Q7SZE8; -.
DR   TreeFam; TF323415; -.
DR   Reactome; R-DRE-1483255; PI Metabolism.
DR   PRO; PR:Q7SZE8; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 22.
DR   Bgee; ENSDARG00000086457; Expressed in early embryo and 31 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; ISS:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   Gene3D; 1.20.1440.160; -; 1.
DR   InterPro; IPR008477; TNFAIP8-like.
DR   InterPro; IPR038355; TNFAIP8_sf.
DR   PANTHER; PTHR12757; PTHR12757; 1.
DR   Pfam; PF05527; DUF758; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Reference proteome.
FT   CHAIN           1..186
FT                   /note="Tumor necrosis factor alpha-induced protein 8-like
FT                   protein 1"
FT                   /id="PRO_0000285727"
FT   COILED          37..70
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   186 AA;  21590 MW;  19A23BAFCCE1A8EE CRC64;
     MDSFSTKNLA LQAQKKLMSK MATKTVANLF IDDTSSEVLD ELYRVTKEYT RNRKEAQKII
     KNLIKMVVKL GVLYRNGQFN NEELALVERF RKKVHTLAMT AVSFYQIDFT FDRRVMSNLL
     NDCRELLHQA INRHLTAKSH ARINHVFNHF ADCDFLATLY GPSEVYRGHL QKICEGVNKM
     LDEGNL