TPC13_CAEEL
ID TPC13_CAEEL Reviewed; 401 AA.
AC Q95QQ2; B2MZA6; Q95QQ3;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Probable trafficking protein particle complex subunit 13 homolog;
GN ORFNames=C56C10.7;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=a;
CC IsoId=Q95QQ2-1; Sequence=Displayed;
CC Name=b;
CC IsoId=Q95QQ2-2; Sequence=VSP_031802;
CC Name=c;
CC IsoId=Q95QQ2-3; Sequence=VSP_038031;
CC -!- SIMILARITY: Belongs to the TRAPPC13 family. {ECO:0000305}.
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DR EMBL; FO080968; CCD68177.1; -; Genomic_DNA.
DR EMBL; FO080968; CCD68178.1; -; Genomic_DNA.
DR EMBL; FO080968; CCD68186.1; -; Genomic_DNA.
DR RefSeq; NP_001129809.1; NM_001136337.2. [Q95QQ2-3]
DR RefSeq; NP_741009.1; NM_171009.4. [Q95QQ2-1]
DR RefSeq; NP_741010.1; NM_171851.6.
DR AlphaFoldDB; Q95QQ2; -.
DR BioGRID; 39427; 3.
DR DIP; DIP-24418N; -.
DR IntAct; Q95QQ2; 3.
DR EPD; Q95QQ2; -.
DR PeptideAtlas; Q95QQ2; -.
DR EnsemblMetazoa; C56C10.7a.1; C56C10.7a.1; WBGene00016964. [Q95QQ2-1]
DR EnsemblMetazoa; C56C10.7a.2; C56C10.7a.2; WBGene00016964. [Q95QQ2-1]
DR EnsemblMetazoa; C56C10.7b.1; C56C10.7b.1; WBGene00016964.
DR EnsemblMetazoa; C56C10.7c.1; C56C10.7c.1; WBGene00016964. [Q95QQ2-3]
DR GeneID; 174089; -.
DR UCSC; C56C10.7a.1; c. elegans.
DR CTD; 174089; -.
DR WormBase; C56C10.7a; CE29739; WBGene00016964; -. [Q95QQ2-1]
DR WormBase; C56C10.7b; CE02572; WBGene00016964; -. [Q95QQ2-2]
DR WormBase; C56C10.7c; CE42577; WBGene00016964; -. [Q95QQ2-3]
DR GeneTree; ENSGT00390000015280; -.
DR InParanoid; Q95QQ2; -.
DR OMA; FKFQVVK; -.
DR OrthoDB; 1608721at2759; -.
DR PhylomeDB; Q95QQ2; -.
DR Reactome; R-CEL-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR PRO; PR:Q95QQ2; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00016964; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:1990072; C:TRAPPIII protein complex; IBA:GO_Central.
DR InterPro; IPR010378; TRAPPC13.
DR PANTHER; PTHR13134; PTHR13134; 1.
DR Pfam; PF06159; DUF974; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..401
FT /note="Probable trafficking protein particle complex
FT subunit 13 homolog"
FT /id="PRO_0000321555"
FT VAR_SEQ 1..158
FT /note="Missing (in isoform c)"
FT /evidence="ECO:0000305"
FT /id="VSP_038031"
FT VAR_SEQ 184..225
FT /note="DNANQDVYLEAQIENTSNANMFLEKVELDPSQHYNVTSIAHE -> VSSNRV
FT LCINVVFFRTMRIKMSTSKPKLKIHQMRICSWKKSSWIQVNIIMLLVSLMST (in
FT isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_031802"
SQ SEQUENCE 401 AA; 44844 MW; 67024AD4CEA27998 CRC64;
MADNPASSSS QQLLALRVMR LARPKFAPVD GFSHDPVDPT GFGELLAGKV SEISKESRQD
LPIGEYLIAP QMFENIYLGE TFTFYVNVVN ESEKTVSSVS LKCELQTSTQ RVVLPCSVQD
ATIESSKCEG QVISHEVKEI GQHILICSVN YKTSNGENMY FRKFFKFPVS KPIDVKTKFY
SAEDNANQDV YLEAQIENTS NANMFLEKVE LDPSQHYNVT SIAHEDEFGD VGKLLKPKDI
RQFLFCLTPA DVHNTLGYKD LTSIGKLDMS WRTSMGEKGR LQTSALQRIA PGYGDVRLSV
EKTPACVDVQ KPFEVSCRLY NCSERALDLQ LRLEQPSNRH LVFCSPSGVS LGQLPPSQHV
DFSLNVFPVT VGIQSISGIR ITDTFTKRIY EHDDIAQIFV S
