ID   TPC13_DROME             Reviewed;         438 AA.
AC   Q95TN1; Q9VL12;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Probable trafficking protein particle complex subunit 13 homolog;
GN   ORFNames=CG4953;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Berkeley; TISSUE=Embryo;
RX   PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA   Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA   Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA   Celniker S.E.;
RT   "A Drosophila full-length cDNA resource.";
RL   Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC   -!- SIMILARITY: Belongs to the TRAPPC13 family. {ECO:0000305}.
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DR   EMBL; AE014134; AAF52893.3; -; Genomic_DNA.
DR   EMBL; AY058665; AAL13894.1; -; mRNA.
DR   RefSeq; NP_609365.3; NM_135521.6.
DR   AlphaFoldDB; Q95TN1; -.
DR   BioGRID; 60461; 2.
DR   STRING; 7227.FBpp0079574; -.
DR   PaxDb; Q95TN1; -.
DR   PRIDE; Q95TN1; -.
DR   DNASU; 34373; -.
DR   EnsemblMetazoa; FBtr0079984; FBpp0079574; FBgn0032204.
DR   GeneID; 34373; -.
DR   KEGG; dme:Dmel_CG4953; -.
DR   UCSC; CG4953-RA; d. melanogaster.
DR   FlyBase; FBgn0032204; CG4953.
DR   VEuPathDB; VectorBase:FBgn0032204; -.
DR   eggNOG; KOG2625; Eukaryota.
DR   GeneTree; ENSGT00390000015280; -.
DR   HOGENOM; CLU_027041_0_0_1; -.
DR   InParanoid; Q95TN1; -.
DR   OMA; FKFQVVK; -.
DR   OrthoDB; 1608721at2759; -.
DR   PhylomeDB; Q95TN1; -.
DR   Reactome; R-DME-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR   BioGRID-ORCS; 34373; 0 hits in 1 CRISPR screen.
DR   GenomeRNAi; 34373; -.
DR   PRO; PR:Q95TN1; -.
DR   Proteomes; UP000000803; Chromosome 2L.
DR   Bgee; FBgn0032204; Expressed in cleaving embryo and 22 other tissues.
DR   Genevisible; Q95TN1; DM.
DR   GO; GO:0005794; C:Golgi apparatus; IDA:FlyBase.
DR   GO; GO:1990072; C:TRAPPIII protein complex; IDA:FlyBase.
DR   GO; GO:0048193; P:Golgi vesicle transport; IC:FlyBase.
DR   InterPro; IPR010378; TRAPPC13.
DR   PANTHER; PTHR13134; PTHR13134; 1.
DR   Pfam; PF06159; DUF974; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..438
FT                   /note="Probable trafficking protein particle complex
FT                   subunit 13 homolog"
FT                   /id="PRO_0000321556"
SQ   SEQUENCE   438 AA;  48683 MW;  29D12AA73FEA5FE2 CRC64;
     MEMVEPDAHL VALKVMRLMR PTLVGLGPVV TCEPTDLVQR FSSSQESDGM SGACAETLAA
     GQVLLLPQSF GSIYLGETFA SYICVHNTTP NPVECVTVKA DLQSNTSRIN LSMHENAKSP
     VVLPPGGTID DVIRYEVKEI GTHILVCEVN YSTPAGYAQS LRKFFKFQVL KPLDVKTKFY
     NAEIDEIYLE AQIQNVTTSP FCLEKVELDG SEDYSVTPLN TLPNGESVFT VKHMLQPNNS
     CQFLYCIKPK GDIAKNVDTL RQFNNVGKLD IVWRSNLGEK GRLQTSQLQR LPFECKTLRL
     EVLDAKNTIK IGTIFTFNCR VTNTSEHPMK LNVRLAAKFS PDSQYTGCAD FMLNLLQSGE
     SAEFPLSVCP SKLGLVKITP LVLTNTLQNE QFTIENVVDV FVVNSDYDND TTTHQNKLIR
     YESAASCLTQ KQVQLQVV