ID   TPC2L_RAT               Reviewed;         139 AA.
AC   B2RYU6;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Trafficking protein particle complex subunit 2-like protein;
GN   Name=Trappc2l;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway;
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Pituitary;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May play a role in vesicular transport from endoplasmic
CC       reticulum to Golgi. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the multisubunit TRAPP (transport protein
CC       particle) complex, which includes at least TRAPPC2, TRAPPC2L, TRAPPC3,
CC       TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and
CC       TRAPPC12. Interacts with the heterodimer TRAPPC3-TRAPPC6A (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000250}.
CC       Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAPP small subunits family. Sedlin
CC       subfamily. {ECO:0000305}.
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DR   EMBL; CH473972; EDL92762.1; -; Genomic_DNA.
DR   EMBL; BC166907; AAI66907.1; -; mRNA.
DR   EMBL; BC166917; AAI66917.1; -; mRNA.
DR   EMBL; BC168734; AAI68734.1; -; mRNA.
DR   RefSeq; NP_001099663.1; NM_001106193.1.
DR   AlphaFoldDB; B2RYU6; -.
DR   SMR; B2RYU6; -.
DR   STRING; 10116.ENSRNOP00000019740; -.
DR   PhosphoSitePlus; B2RYU6; -.
DR   jPOST; B2RYU6; -.
DR   PaxDb; B2RYU6; -.
DR   PeptideAtlas; B2RYU6; -.
DR   Ensembl; ENSRNOT00000019740; ENSRNOP00000019740; ENSRNOG00000014581.
DR   GeneID; 292074; -.
DR   KEGG; rno:292074; -.
DR   UCSC; RGD:1304906; rat.
DR   CTD; 51693; -.
DR   RGD; 1304906; Trappc2l.
DR   eggNOG; KOG3444; Eukaryota.
DR   GeneTree; ENSGT00510000047505; -.
DR   HOGENOM; CLU_085828_2_3_1; -.
DR   InParanoid; B2RYU6; -.
DR   OMA; IAHTSID; -.
DR   OrthoDB; 1549524at2759; -.
DR   PhylomeDB; B2RYU6; -.
DR   TreeFam; TF323920; -.
DR   Reactome; R-RNO-204005; COPII-mediated vesicle transport.
DR   Reactome; R-RNO-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR   PRO; PR:B2RYU6; -.
DR   Proteomes; UP000002494; Chromosome 19.
DR   Proteomes; UP000234681; Chromosome 19.
DR   Bgee; ENSRNOG00000014581; Expressed in pancreas and 19 other tissues.
DR   Genevisible; B2RYU6; RN.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030008; C:TRAPP complex; ISO:RGD.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   CDD; cd14854; TRAPPC2L; 1.
DR   InterPro; IPR011012; Longin-like_dom_sf.
DR   InterPro; IPR006722; Sedlin.
DR   InterPro; IPR007233; TRAPPC.
DR   InterPro; IPR044760; TRAPPC2L.
DR   PANTHER; PTHR12403; PTHR12403; 1.
DR   Pfam; PF04628; Sedlin_N; 1.
DR   SMART; SM01399; Sybindin; 1.
DR   SUPFAM; SSF64356; SSF64356; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus;
KW   Reference proteome; Transport.
FT   CHAIN           1..139
FT                   /note="Trafficking protein particle complex subunit 2-like
FT                   protein"
FT                   /id="PRO_0000379774"
SQ   SEQUENCE   139 AA;  16032 MW;  027C7A0849B96662 CRC64;
     MAVCIAVIAK ENYPLYIRST PTENELKFHY MVHTSLDVVD EKISAMGKAL VDQRELYLGL
     LYPTEDYKVY GYVTNSKVKF VMVVDSSNTA LRDNEIRSMF RKLHNSYTDV MCNPFYNPGD
     RIQSRAFDTM VTSMMVQVC