ID   TPC6A_BOVIN             Reviewed;         159 AA.
AC   Q3T086;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Trafficking protein particle complex subunit 6A {ECO:0000250|UniProtKB:O75865};
DE            Short=TRAPP complex subunit 6A;
GN   Name=TRAPPC6A {ECO:0000250|UniProtKB:O75865};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in vesicular transport during the biogenesis
CC       of melanosomes. {ECO:0000250|UniProtKB:Q78XR0}.
CC   -!- SUBUNIT: Part of the multisubunit transport protein particle (TRAPP)
CC       complex. Heterodimer with TRAPPC3 (By similarity). The heterodimer
CC       TRAPPC3-TRAPPC6A interacts with TRAPPC2L. Interacts with TRAPPC2L (By
CC       similarity). {ECO:0000250|UniProtKB:O75865}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network {ECO:0000250}.
CC       Endoplasmic reticulum {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAPP small subunits family. BET3 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; BC102525; AAI02526.1; -; mRNA.
DR   RefSeq; NP_001029592.1; NM_001034420.2.
DR   AlphaFoldDB; Q3T086; -.
DR   SMR; Q3T086; -.
DR   STRING; 9913.ENSBTAP00000009288; -.
DR   PaxDb; Q3T086; -.
DR   PRIDE; Q3T086; -.
DR   Ensembl; ENSBTAT00000009288; ENSBTAP00000009288; ENSBTAG00000007065.
DR   GeneID; 512261; -.
DR   KEGG; bta:512261; -.
DR   CTD; 79090; -.
DR   VEuPathDB; HostDB:ENSBTAG00000007065; -.
DR   VGNC; VGNC:36292; TRAPPC6A.
DR   eggNOG; KOG3316; Eukaryota.
DR   GeneTree; ENSGT00390000012948; -.
DR   HOGENOM; CLU_076409_3_1_1; -.
DR   InParanoid; Q3T086; -.
DR   OMA; QVVIQKA; -.
DR   OrthoDB; 1590219at2759; -.
DR   TreeFam; TF313010; -.
DR   Reactome; R-BTA-204005; COPII-mediated vesicle transport.
DR   Reactome; R-BTA-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR   Proteomes; UP000009136; Chromosome 18.
DR   Bgee; ENSBTAG00000007065; Expressed in olfactory segment of nasal mucosa and 105 other tissues.
DR   GO; GO:0005801; C:cis-Golgi network; IBA:GO_Central.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR   GO; GO:0030008; C:TRAPP complex; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:1903232; P:melanosome assembly; IBA:GO_Central.
DR   GO; GO:0043087; P:regulation of GTPase activity; IEA:InterPro.
DR   CDD; cd14944; TRAPPC6A_Trs33; 1.
DR   InterPro; IPR024096; NO_sig/Golgi_transp_ligand-bd.
DR   InterPro; IPR007194; TRAPP_component.
DR   InterPro; IPR037992; TRAPPC6/Trs33.
DR   PANTHER; PTHR12817; PTHR12817; 1.
DR   Pfam; PF04051; TRAPP; 1.
DR   SUPFAM; SSF111126; SSF111126; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Phosphoprotein;
KW   Reference proteome; Transport.
FT   CHAIN           1..159
FT                   /note="Trafficking protein particle complex subunit 6A"
FT                   /id="PRO_0000244538"
FT   MOD_RES         33
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q78XR0"
SQ   SEQUENCE   159 AA;  17640 MW;  C0899428EDB85536 CRC64;
     MADPALFEFL HTEMVAELWA QDPDPGPGGQ KTSLLVLEGM GFRVGQALGE RLPRETLTFR
     EELDILKFLC KDLWVAVFHK QMDSLRTNHQ GTYVLQDNSF PLLVRMASGL QYLEEAPKFL
     AFTCGLLRGT LSTLGVKSLV TASVAALPAC KFQVVIQKL