BTUC_SALPB
ID BTUC_SALPB Reviewed; 326 AA.
AC A9N235;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 1.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Vitamin B12 import system permease protein BtuC {ECO:0000255|HAMAP-Rule:MF_01004};
GN Name=btuC {ECO:0000255|HAMAP-Rule:MF_01004}; OrderedLocusNames=SPAB_01997;
OS Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=1016998;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1250 / SPB7;
RG The Salmonella enterica serovar Paratyphi B Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the ABC transporter complex BtuCDF involved in
CC vitamin B12 import. Involved in the translocation of the substrate
CC across the membrane. {ECO:0000255|HAMAP-Rule:MF_01004}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (BtuD),
CC two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).
CC {ECO:0000255|HAMAP-Rule:MF_01004}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01004}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01004}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. FecCD subfamily. {ECO:0000255|HAMAP-Rule:MF_01004}.
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DR EMBL; CP000886; ABX67384.1; -; Genomic_DNA.
DR RefSeq; WP_000954984.1; NC_010102.1.
DR AlphaFoldDB; A9N235; -.
DR SMR; A9N235; -.
DR KEGG; spq:SPAB_01997; -.
DR PATRIC; fig|1016998.12.peg.1885; -.
DR HOGENOM; CLU_013016_0_3_6; -.
DR OMA; AMVYWSF; -.
DR BioCyc; SENT1016998:SPAB_RS08145-MON; -.
DR Proteomes; UP000008556; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0090482; F:vitamin transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015889; P:cobalamin transport; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.3470.10; -; 1.
DR HAMAP; MF_01004; BtuC; 1.
DR InterPro; IPR037294; ABC_BtuC-like.
DR InterPro; IPR023691; ABC_transptr_BtuC.
DR InterPro; IPR000522; ABC_transptr_permease_BtuC.
DR PANTHER; PTHR30472; PTHR30472; 1.
DR Pfam; PF01032; FecCD; 1.
DR SUPFAM; SSF81345; SSF81345; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..326
FT /note="Vitamin B12 import system permease protein BtuC"
FT /id="PRO_1000083957"
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01004"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01004"
FT TRANSMEM 88..108
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01004"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01004"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01004"
FT TRANSMEM 184..204
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01004"
FT TRANSMEM 240..260
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01004"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01004"
FT TRANSMEM 302..322
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01004"
SQ SEQUENCE 326 AA; 34884 MW; 362BB92622133BC4 CRC64;
MLTFARQQQR RNVRWLLSLS LLVLLATLLS LCAGEQWIAP GDWLSARGEL FVWQIRLPRT
LAVLLVGAAL ALSGAVMQAL FENPLAEPGL LGVSNGAGVG LIAAVLLGQG QLPGWALGLC
AIAGALIITL ILLRFARRHL STSRLLLAGV ALGIICSALM TWAIYFSTSF DLRQLMYWMM
GGFGGVDWQQ SWLMIALIPV LIWICCQSQP LNMLALGETS ARQLGLPLWF WRNLLVVATG
WMVGVSVAMA GAIGFIGLVI PHILRLCGLT DHRVLLPGCA LAGAIALLLA DVVARLALAS
AELPIGVVTA TLGAPVFIWL LLKSAR