ID   TPM1_BIOGL              Reviewed;         284 AA.
AC   P42636;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Tropomyosin-1;
DE   AltName: Full=Bg 39;
DE   AltName: Full=Tropomyosin I;
DE            Short=BgTMI;
DE            Short=TMI;
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2090946; DOI=10.1016/0166-6851(90)90149-g;
RA   Dissous C., Torpier G., Duvaux-Miret O., Capron A.;
RT   "Structural homology of tropomyosins from the human trematode Schistosoma
RT   mansoni and its intermediate host Biomphalaria glabrata.";
RL   Mol. Biochem. Parasitol. 43:245-255(1990).
CC   -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC       a central role in the calcium dependent regulation of muscle
CC       contraction.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- DOMAIN: The molecule is in a coiled coil structure that is formed by 2
CC       polypeptide chains. The sequence exhibits a prominent seven-residues
CC       periodicity.
CC   -!- SIMILARITY: Belongs to the tropomyosin family. {ECO:0000305}.
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DR   EMBL; M85199; AAA27817.1; -; mRNA.
DR   PIR; A33085; A33085.
DR   AlphaFoldDB; P42636; -.
DR   SMR; P42636; -.
DR   STRING; 6526.P42636; -.
DR   VEuPathDB; VectorBase:BGLB011792; -.
DR   Proteomes; UP000076420; Genome assembly.
DR   InterPro; IPR000533; Tropomyosin.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
DR   PROSITE; PS00326; TROPOMYOSIN; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Repeat.
FT   CHAIN           1..284
FT                   /note="Tropomyosin-1"
FT                   /id="PRO_0000205662"
FT   REGION          103..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1..284
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   284 AA;  32716 MW;  13735417CE449AE8 CRC64;
     MDAIKKKMLA MKMEKENAID RAEQMEQKLR DVEETKNKLE EEFNNLQNKF SNLQNDFDTA
     NEGLTEAQTK LEASEKHVAE LESDTAGLNR RIQLLEEDLE RSEERLQSAT EKLEEASKAA
     DESERGRKVL ESRSLADDER LDGLEAQLKE AKYIAEDAER KYDEAARKLA ITEVDLERAE
     ARLEAAEAKV WELDEELHIV GNNIKTLSIQ NDQASQREDS YQETIRDLTQ RLKDAENRAT
     EAERTVSKLQ KEVDRLEDEL LAEKERYKSI SDELDSTFAE LAGY