TPM1_HYDVU
ID TPM1_HYDVU Reviewed; 253 AA.
AC P39921;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 2.
DT 03-AUG-2022, entry version 49.
DE RecName: Full=Tropomyosin-1;
DE AltName: Full=Tropomyosin I;
GN Name=TROP1;
OS Hydra vulgaris (Hydra) (Hydra attenuata).
OC Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC Aplanulata; Hydridae; Hydra.
OX NCBI_TaxID=6087;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=7962184; DOI=10.1242/jcs.107.6.1403;
RA Lopez de Haro M.S., Salgado L.M., David C.N., Bosch T.C.G.;
RT "Hydra tropomyosin TROP1 is expressed in head-specific epithelial cells and
RT is a major component of the cytoskeletal structure that anchors
RT nematocytes.";
RL J. Cell Sci. 107:1403-1411(1994).
CC -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC a central role in the calcium dependent regulation of muscle
CC contraction.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- DOMAIN: The molecule is in a coiled coil structure that is formed by 2
CC polypeptide chains. The sequence exhibits a prominent seven-residues
CC periodicity.
CC -!- SIMILARITY: Belongs to the tropomyosin family. {ECO:0000305}.
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DR EMBL; X70840; CAA50188.1; -; mRNA.
DR PIR; S32041; S32041.
DR RefSeq; NP_001296670.1; NM_001309741.1.
DR AlphaFoldDB; P39921; -.
DR SMR; P39921; -.
DR GeneID; 100215665; -.
DR KEGG; hmg:100215665; -.
DR Proteomes; UP000694840; Unplaced.
DR InterPro; IPR000533; Tropomyosin.
DR Pfam; PF00261; Tropomyosin; 1.
DR PRINTS; PR00194; TROPOMYOSIN.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome; Repeat.
FT CHAIN 1..253
FT /note="Tropomyosin-1"
FT /id="PRO_0000205659"
FT COILED 7..253
FT /evidence="ECO:0000255"
SQ SEQUENCE 253 AA; 29217 MW; 7C5C065816E87D01 CRC64;
MVVETGVNKL VRLQGKIEGI NSKIDEADLR RANAKSSIVE ASSRLEKAEG EVASFQRRIR
LVQQNLNDVT ERAQMLQSKV DNLEDVSESV KQARNQYEEE EAESDEKIQN LEEEVKVKKR
ELEENEIKLR EKERRNVVVH RDIEAATVKA DAIEKRIEIL ENTIKNGLES IKDLEEREGR
TNEKENNIAE QISFLDNKFK EVEIRIEAAE RNCNVLEHNI KETSEEIKTW KHNTHAIEEE
IAAMDDVGDD DTQ