ID   TPM1_HYDVU              Reviewed;         253 AA.
AC   P39921;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 2.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Tropomyosin-1;
DE   AltName: Full=Tropomyosin I;
GN   Name=TROP1;
OS   Hydra vulgaris (Hydra) (Hydra attenuata).
OC   Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC   Aplanulata; Hydridae; Hydra.
OX   NCBI_TaxID=6087;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=7962184; DOI=10.1242/jcs.107.6.1403;
RA   Lopez de Haro M.S., Salgado L.M., David C.N., Bosch T.C.G.;
RT   "Hydra tropomyosin TROP1 is expressed in head-specific epithelial cells and
RT   is a major component of the cytoskeletal structure that anchors
RT   nematocytes.";
RL   J. Cell Sci. 107:1403-1411(1994).
CC   -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC       a central role in the calcium dependent regulation of muscle
CC       contraction.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- DOMAIN: The molecule is in a coiled coil structure that is formed by 2
CC       polypeptide chains. The sequence exhibits a prominent seven-residues
CC       periodicity.
CC   -!- SIMILARITY: Belongs to the tropomyosin family. {ECO:0000305}.
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DR   EMBL; X70840; CAA50188.1; -; mRNA.
DR   PIR; S32041; S32041.
DR   RefSeq; NP_001296670.1; NM_001309741.1.
DR   AlphaFoldDB; P39921; -.
DR   SMR; P39921; -.
DR   GeneID; 100215665; -.
DR   KEGG; hmg:100215665; -.
DR   Proteomes; UP000694840; Unplaced.
DR   InterPro; IPR000533; Tropomyosin.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome; Repeat.
FT   CHAIN           1..253
FT                   /note="Tropomyosin-1"
FT                   /id="PRO_0000205659"
FT   COILED          7..253
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   253 AA;  29217 MW;  7C5C065816E87D01 CRC64;
     MVVETGVNKL VRLQGKIEGI NSKIDEADLR RANAKSSIVE ASSRLEKAEG EVASFQRRIR
     LVQQNLNDVT ERAQMLQSKV DNLEDVSESV KQARNQYEEE EAESDEKIQN LEEEVKVKKR
     ELEENEIKLR EKERRNVVVH RDIEAATVKA DAIEKRIEIL ENTIKNGLES IKDLEEREGR
     TNEKENNIAE QISFLDNKFK EVEIRIEAAE RNCNVLEHNI KETSEEIKTW KHNTHAIEEE
     IAAMDDVGDD DTQ