ID   TPM1_SOLLC              Reviewed;         238 AA.
AC   Q01591;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Osmotin-like protein TPM-1;
DE   AltName: Full=PR P23;
DE   Flags: Precursor; Fragment;
GN   Name=TPM-1;
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Rio Grande; TISSUE=Leaf;
RX   PubMed=1463856; DOI=10.1007/bf00028909;
RA   Ruiz-Medrano R., Jimenez-Moraila B., Herrera-Estrella L.,
RA   Rivera-Bustamante R.F.;
RT   "Nucleotide sequence of an osmotin-like cDNA induced in tomato during
RT   viroid infection.";
RL   Plant Mol. Biol. 20:1199-1202(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 6-238.
RC   STRAIN=cv. Rutgers; TISSUE=Leaf;
RX   PubMed=8278538; DOI=10.1104/pp.102.3.939;
RA   Rodrigo I., Vera P., Tornero P., Hernandez-Yago J., Conejero V.;
RT   "cDNA cloning of viroid-induced tomato pathogenesis-related protein P23.
RT   Characterization as a vacuolar antifungal factor.";
RL   Plant Physiol. 102:939-945(1993).
CC   -!- FUNCTION: Antifungal protein.
CC   -!- INDUCTION: By viroid infection.
CC   -!- SIMILARITY: Belongs to the thaumatin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00699}.
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DR   EMBL; X66416; CAA47047.1; -; mRNA.
DR   EMBL; X70787; CAA50059.1; -; mRNA.
DR   PIR; PQ0742; S31829.
DR   PIR; S28001; S28001.
DR   AlphaFoldDB; Q01591; -.
DR   SMR; Q01591; -.
DR   STRING; 4081.Solyc08g080650.1.1; -.
DR   Allergome; 9063; Sola l TLP.
DR   PaxDb; Q01591; -.
DR   PRIDE; Q01591; -.
DR   eggNOG; ENOG502QV4N; Eukaryota.
DR   InParanoid; Q01591; -.
DR   Proteomes; UP000004994; Unplaced.
DR   ExpressionAtlas; Q01591; baseline and differential.
DR   GO; GO:0006952; P:defense response; IBA:GO_Central.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.110.10; -; 1.
DR   InterPro; IPR037176; Osmotin/thaumatin-like_sf.
DR   InterPro; IPR001938; Thaumatin.
DR   InterPro; IPR017949; Thaumatin_CS.
DR   PANTHER; PTHR31048; PTHR31048; 1.
DR   Pfam; PF00314; Thaumatin; 1.
DR   PIRSF; PIRSF002703; Thaumatin; 1.
DR   PRINTS; PR00347; THAUMATIN.
DR   SMART; SM00205; THN; 1.
DR   SUPFAM; SSF49870; SSF49870; 1.
DR   PROSITE; PS00316; THAUMATIN_1; 1.
DR   PROSITE; PS51367; THAUMATIN_2; 1.
PE   2: Evidence at transcript level;
KW   Antimicrobial; Disulfide bond; Fungicide; Pathogenesis-related protein;
KW   Plant defense; Reference proteome; Signal.
FT   SIGNAL          <1..13
FT                   /evidence="ECO:0000255"
FT   CHAIN           14..238
FT                   /note="Osmotin-like protein TPM-1"
FT                   /id="PRO_0000034045"
FT   DISULFID        22..217
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        64..74
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        79..85
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        133..205
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        138..188
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        146..156
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        160..169
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        170..175
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   CONFLICT        69
FT                   /note="D -> A (in Ref. 2; CAA50059)"
FT                   /evidence="ECO:0000305"
FT   NON_TER         1
SQ   SEQUENCE   238 AA;  25840 MW;  1BAE7CD44ABE4419 CRC64;
     FFFLLAFVTY TYAATFEVRN NCPYTVWAAS TPIGGGRRLD RGQTWVINAP RGTKMARIWG
     RTNCNFDGDG RGSCQTGDCG GVLQCTGWGK PPNTLAEYAL DQFSNLDFWD ISLVDGFNIP
     MTFAPTNPSG GKCHAIHCTA NINGECPGSL RVPGGCNNPC TTFGGQQYCC TQGPCGPTDL
     SRFFKQRCPD AYSYPQDDPT STFTCPSGST NYRVVFCPNG VTSPNFPLEM PSSDEEAK