ID   TPM_ECHMU               Reviewed;         284 AA.
AC   Q95PU1;
DT   25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Tropomyosin;
OS   Echinococcus multilocularis (Fox tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX   NCBI_TaxID=6211;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Hubert K., Frosch M., Brehm K.;
RT   "Characterisation of a E. multilocularis tropomyosin encoding mRNA.";
RL   Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC       a central role in the calcium dependent regulation of muscle
CC       contraction.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- DOMAIN: The molecule is in a coiled coil structure that is formed by 2
CC       polypeptide chains. The sequence exhibits a prominent seven-residues
CC       periodicity.
CC   -!- SIMILARITY: Belongs to the tropomyosin family. {ECO:0000305}.
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DR   EMBL; AJ314792; CAC85552.1; -; mRNA.
DR   AlphaFoldDB; Q95PU1; -.
DR   SMR; Q95PU1; -.
DR   eggNOG; KOG1003; Eukaryota.
DR   OMA; TEKRATN; -.
DR   InterPro; IPR000533; Tropomyosin.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
PE   2: Evidence at transcript level;
KW   Coiled coil; Repeat.
FT   CHAIN           1..284
FT                   /note="Tropomyosin"
FT                   /id="PRO_0000205653"
FT   REGION          97..140
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1..284
FT   COMPBIAS        111..140
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   284 AA;  32987 MW;  01431F074BF8A73A CRC64;
     MDSIKKKMMA MKLEKENALE KAINLENQLK EKAKDFEKKE EEMNDWLSKV KNIQTEVDTV
     QESLQEAISK LEETEKRATN AEAEVAAMTR RIRLLEEDFE QSSGRLTETS TKLDDASKAA
     EESERNRKTL ETRSISDDER MAQLEEQVKE AKYIAEDAER KYDEAARRLA VTEVDLERAE
     SRLETSESKI VELEEELRIV GNNMKSLEVS EQESLQREES YEETIRDLTE RLKTAEQRAA
     EAERQVSKLQ NEVDRLEDEL LSEKERYRAI SGELDTTFAE LTSF