ID   TPM_HAELO               Reviewed;         284 AA.
AC   Q8IT89;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=Tropomyosin;
OS   Haemaphysalis longicornis (Bush tick).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Haemaphysalinae;
OC   Haemaphysalis.
OX   NCBI_TaxID=44386;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Lee I.-Y., Jeong K.Y., Lee W.-J., Lee W.K.;
RT   "cDNA sequence encoding Haemaphysalis longicornis tropomyosin.";
RL   Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC       a central role in the calcium dependent regulation of muscle
CC       contraction. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- DOMAIN: The molecule is in a coiled coil structure that is formed by 2
CC       polypeptide chains. The sequence exhibits a prominent seven-residues
CC       periodicity.
CC   -!- SIMILARITY: Belongs to the tropomyosin family. {ECO:0000305}.
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DR   EMBL; AF534184; AAN05633.1; -; mRNA.
DR   AlphaFoldDB; Q8IT89; -.
DR   SMR; Q8IT89; -.
DR   Allergome; 4187; Hae l 7.
DR   Allergome; 4188; Hae l 7.0101.
DR   PRIDE; Q8IT89; -.
DR   InterPro; IPR000533; Tropomyosin.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
PE   2: Evidence at transcript level;
KW   Coiled coil; Repeat.
FT   CHAIN           1..284
FT                   /note="Tropomyosin"
FT                   /id="PRO_0000205680"
FT   REGION          1..41
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1..284
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   284 AA;  32872 MW;  7EA8AEC3DFD228DF CRC64;
     MDAIKKKMQA MKLEKDNAVD RAETAEQQSR DAALRAEKAE EEVRSLQKKI QQIENELDQV
     QEQLSQANSK LEEKDKALQA AEAEVAAHNR RIQLLEEDLE RSEERLKIAT QKLEEASQAA
     DESERMRKML EHRSITDEER MDGLEGQLKE ARTMAEDADR KYDEVARKLA MVEADLERAE
     ERAETGETKI VELEEELRVV GNNLKSLEVS EEKALQKEET YEGQIRQMTS RLQEAEARAE
     FAERSVQKLQ KEVDRLEDEL VQEKEKYKAI SDELDQTFSE LTGY