ID   TPM_LOCMI               Reviewed;         283 AA.
AC   P31816;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Tropomyosin;
OS   Locusta migratoria (Migratory locust).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC   Acridoidea; Acrididae; Oedipodinae; Locusta.
OX   NCBI_TaxID=7004;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RA   Krieger J., Raming K., Knipper M., Grau M., Mertens S., Breer H.;
RT   "Cloning, sequencing and expression of locust tropomyosin.";
RL   Insect Biochem. 20:173-184(1990).
CC   -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC       a central role in the calcium dependent regulation of muscle
CC       contraction.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- DOMAIN: The molecule is in a coiled coil structure that is formed by 2
CC       polypeptide chains. The sequence exhibits a prominent seven-residues
CC       periodicity.
CC   -!- SIMILARITY: Belongs to the tropomyosin family. {ECO:0000305}.
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DR   PIR; A60364; A60364.
DR   AlphaFoldDB; P31816; -.
DR   SMR; P31816; -.
DR   Allergome; 4200; Loc m 7.
DR   Allergome; 4201; Loc m 7.0101.
DR   InterPro; IPR000533; Tropomyosin.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
DR   PROSITE; PS00326; TROPOMYOSIN; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Repeat.
FT   CHAIN           1..283
FT                   /note="Tropomyosin"
FT                   /id="PRO_0000205688"
FT   COILED          1..283
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   283 AA;  32439 MW;  8C9E25EFEA664C0A CRC64;
     MDAIKKKMQA MKLEKDNALD RALLCEQQAR DANLRAEKAE EEARALQKKI QTIENDLDQT
     QESLGQVMAK LEEKEKALQN AESEVAALNR RIQLLEEDLE RSEERLATAT AKLAEASQAA
     DESERARKIL ENRSLADEER MDALENQLKE ARFLAEEADK KYDEVARKLA MVEADLERAE
     ERAEAGESKI VELEEELRVV GNNLKSLEVS EEKANQREEE ISNRLRTLTT RLKEAEARAE
     FAERSVQKLQ KEVDRLEDEL VIEKEKYKII GDDLDSAFVE LIL