ID   TPM_SCHHA               Reviewed;         284 AA.
AC   Q26503;
DT   16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Tropomyosin;
OS   Schistosoma haematobium (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6185;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Nicholson L.J., Karim A.M., Loverde P.T.;
RT   "Comparison of the amino acid sequences for Schistosoma haematobium
RT   tropomyosin and S. japonicum tropomyosin with that of S. mansoni
RT   tropomyosin.";
RL   Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC       a central role in the calcium dependent regulation of muscle
CC       contraction.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- DOMAIN: The molecule is in a coiled coil structure that is formed by 2
CC       polypeptide chains. The sequence exhibits a prominent seven-residues
CC       periodicity.
CC   -!- SIMILARITY: Belongs to the tropomyosin family. {ECO:0000305}.
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DR   EMBL; L76202; AAA88530.1; -; mRNA.
DR   AlphaFoldDB; Q26503; -.
DR   SMR; Q26503; -.
DR   PRIDE; Q26503; -.
DR   InterPro; IPR000533; Tropomyosin.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
DR   PROSITE; PS00326; TROPOMYOSIN; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Repeat.
FT   CHAIN           1..284
FT                   /note="Tropomyosin"
FT                   /id="PRO_0000205654"
FT   REGION          111..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1..284
SQ   SEQUENCE   284 AA;  32982 MW;  8E0FAA7EA9ABD446 CRC64;
     MDGIKKKMIA MKLEKENAME RAVQYEELLK KKEEEREKRE SEIAELNTKM KQAQIDCDEV
     QETLQEQMNK LEETDKRATN AEAEVAAMTR RIRLLEEDLE VSSSRLTETL TKLEEASKTA
     EESERGRKDL EIRSIADDER LNQLEDQQKE AKYIAEDADR KYDEAARKLA IAEVDFKRAE
     ARLEAAESKI VELEEELRVI GNNMKALEIS EQESAQREES YEETIRDLTE RLKAAEQRAT
     EAERQVSKLQ NEVDHLEDDL LAEKERYKAL SGELDQTFAE LTGY