ID   TPM_TRIPS               Reviewed;         284 AA.
AC   Q8WR63;
DT   16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=Tropomyosin;
OS   Trichinella pseudospiralis (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=6337;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Nakada T., Nagano I., Takahashi Y.;
RT   "Molecular cloning and expression of the full length tropomyosin gene from
RT   Trichinella pseudospiralis.";
RL   Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC       a central role in the calcium dependent regulation of muscle
CC       contraction. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- DOMAIN: The molecule is in a coiled coil structure that is formed by 2
CC       polypeptide chains. The sequence exhibits a prominent seven-residues
CC       periodicity.
CC   -!- SIMILARITY: Belongs to the tropomyosin family. {ECO:0000305}.
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DR   EMBL; AF453521; AAL41024.1; -; mRNA.
DR   AlphaFoldDB; Q8WR63; -.
DR   SMR; Q8WR63; -.
DR   InterPro; IPR000533; Tropomyosin.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
DR   PROSITE; PS00326; TROPOMYOSIN; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Repeat.
FT   CHAIN           1..284
FT                   /note="Tropomyosin"
FT                   /id="PRO_0000205649"
FT   REGION          1..47
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1..284
SQ   SEQUENCE   284 AA;  33318 MW;  F5DDA6A2C3FE4420 CRC64;
     MDAIKKKMQA MKIEKDNAMD RADAAEEKAR QQQERVEKLE EELRDTQKKM MQVENELDKA
     QEELTGANAQ LEEKEKKVQE AEAEVAALNR RIQLLEEDFE RAEERLKIAT EKLEEASQTA
     DESERVRKVM ENRSLQDEER VYQLEAQLKE AQLLAEEADR KYDEVARKLA MVEADLERAE
     ERAEAGENKI VELEEELRVV GNNLKSLEVS EEKALQREDS YEEQIRLLTQ RLKEAETRAE
     FAERSVQKLQ KEVDRLEDEL VHEKEKYKAI SEELDQTFQE LSGY