ID   TPM_TURCO               Reviewed;         146 AA.
AC   Q7M3Y8;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Tropomyosin;
DE   AltName: Full=Major allergen Tur c 1;
DE   AltName: Allergen=Tur c 1;
DE   Flags: Fragments;
OS   Turbo cornutus (Horned turban) (Battilus cornutus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Vetigastropoda; Trochida; Trochoidea; Turbinidae; Turbo; Batillus.
OX   NCBI_TaxID=63673;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Muscle;
RX   PubMed=9720216; DOI=10.1271/bbb.62.1337;
RA   Ishikawa M., Ishida M., Shimakura K., Nagashima Y., Shiomi K.;
RT   "Purification and IgE-binding epitopes of a major allergen in the gastropod
RT   Turbo cornutus.";
RL   Biosci. Biotechnol. Biochem. 62:1337-1343(1998).
CC   -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC       a central role in the calcium dependent regulation of muscle
CC       contraction.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- DOMAIN: The molecule is in a coiled coil structure that is formed by 2
CC       polypeptide chains. The sequence exhibits a prominent seven-residues
CC       periodicity.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
CC   -!- SIMILARITY: Belongs to the tropomyosin family. {ECO:0000305}.
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DR   PIR; JE0229; JE0229.
DR   AlphaFoldDB; Q7M3Y8; -.
DR   SMR; Q7M3Y8; -.
DR   Allergome; 656; Tur c 1.
DR   InterPro; IPR000533; Tropomyosin.
DR   Pfam; PF00261; Tropomyosin; 1.
PE   1: Evidence at protein level;
KW   Allergen; Coiled coil; Direct protein sequencing; Repeat.
FT   CHAIN           <1..146
FT                   /note="Tropomyosin"
FT                   /id="PRO_0000205672"
FT   REGION          76..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          <1..146
FT                   /evidence="ECO:0000250"
FT   NON_CONS        20..21
FT                   /evidence="ECO:0000305"
FT   NON_CONS        47..48
FT                   /evidence="ECO:0000305"
FT   NON_CONS        55..56
FT                   /evidence="ECO:0000305"
FT   NON_CONS        77..78
FT                   /evidence="ECO:0000305"
FT   NON_CONS        106..107
FT                   /evidence="ECO:0000305"
FT   NON_TER         1
SQ   SEQUENCE   146 AA;  16839 MW;  CAA859DA08A320F6 CRC64;
     AANLENDFDN VNEQLQDALS KITLLEEDLE RNEERLQTAT ERLEEASKYI AEDAERKLAI
     TEVDLERAEA RLEAAEAKSL EISEQEASQR EDSYEETIRD LTQRLKTVSK LQKEVDRLED
     ELLAEKEKYK AISDELDQTF AELAGY