ID   TPP8_ORYSJ              Reviewed;         500 AA.
AC   Q0DDI1; Q67VY4;
DT   13-JUN-2012, integrated into UniProtKB/Swiss-Prot.
DT   13-JUN-2012, sequence version 3.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Probable trehalose-phosphate phosphatase 8;
DE            Short=OsTPP8;
DE            EC=3.1.3.12;
DE   AltName: Full=Trehalose 6-phosphate phosphatase;
GN   Name=TPP8; OrderedLocusNames=Os06g0222100, LOC_Os06g11840;
GN   ORFNames=P0516A04.26;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RC   STRAIN=cv. Yukihikari;
RX   PubMed=16240171; DOI=10.1007/s11103-005-7404-4;
RA   Pramanik M.H., Imai R.;
RT   "Functional identification of a trehalose 6-phosphate phosphatase gene that
RT   is involved in transient induction of trehalose biosynthesis during
RT   chilling stress in rice.";
RL   Plant Mol. Biol. 58:751-762(2005).
CC   -!- FUNCTION: Removes the phosphate from trehalose 6-phosphate to produce
CC       free trehalose. Trehalose accumulation in plant may improve abiotic
CC       stress tolerance (By similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha,alpha-trehalose 6-phosphate + H2O = alpha,alpha-
CC         trehalose + phosphate; Xref=Rhea:RHEA:23420, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:16551, ChEBI:CHEBI:43474, ChEBI:CHEBI:58429; EC=3.1.3.12;
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC         Evidence={ECO:0000250};
CC   -!- PATHWAY: Glycan biosynthesis; trehalose biosynthesis.
CC   -!- SIMILARITY: Belongs to the trehalose phosphatase family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAD37685.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAF19092.2; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AP004727; BAD37685.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008212; BAF19092.2; ALT_INIT; Genomic_DNA.
DR   EMBL; AP014962; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; Q0DDI1; -.
DR   SMR; Q0DDI1; -.
DR   STRING; 39947.Q0DDI1; -.
DR   PaxDb; Q0DDI1; -.
DR   PRIDE; Q0DDI1; -.
DR   eggNOG; KOG1050; Eukaryota.
DR   InParanoid; Q0DDI1; -.
DR   UniPathway; UPA00299; -.
DR   Proteomes; UP000000763; Chromosome 6.
DR   Proteomes; UP000059680; Chromosome 6.
DR   GO; GO:0004805; F:trehalose-phosphatase activity; IBA:GO_Central.
DR   GO; GO:0005992; P:trehalose biosynthetic process; IBA:GO_Central.
DR   Gene3D; 3.40.50.1000; -; 1.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR006379; HAD-SF_hydro_IIB.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR044651; OTSB-like.
DR   InterPro; IPR003337; Trehalose_PPase.
DR   PANTHER; PTHR43768; PTHR43768; 1.
DR   Pfam; PF02358; Trehalose_PPase; 1.
DR   SUPFAM; SSF56784; SSF56784; 1.
DR   TIGRFAMs; TIGR01484; HAD-SF-IIB; 1.
DR   TIGRFAMs; TIGR00685; T6PP; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Reference proteome; Stress response.
FT   CHAIN           1..500
FT                   /note="Probable trehalose-phosphate phosphatase 8"
FT                   /id="PRO_0000417660"
SQ   SEQUENCE   500 AA;  53443 MW;  B3EC9ADE2D5A6227 CRC64;
     MTNQDVVMPD IAAAAAMPGS SGRAPLFACR GAAAVSASSM LGGGGAAYQA AVVAHVAPVP
     AIRPCASWVV EAMRASSPTR PAAAAVDAEY DAWTQRKHPS ALGSFEQVAA AASGKRVVVF
     LDYDGTLSPI VADPDMAFMS DEMRAAVRDV AEHFPAAIVT GRCVDKVQSF VGLPELYYAG
     SHGMDIKGPS SNEEEDTKIL LQPAREFLPV INKAYKALME KTKSTPGARV ENNKFCLSVH
     FRCVDEKRWN PLAEQVKAVL RDYPELKLTQ GRKVLEIRPS IMWDKGKAVE FLLKSLGFDD
     DRRDVLPVYI GDDRTDEDAF KVLRKRGQGL GILVSKCAKE TDASYSLQDP AEKYTNAGAH
     VFVTMLLTVV FTAAVALALV NAVNSHDFAA HLAGVDCRMG LAGPVRCPAS GFVELLVLAL
     HVVRCVLAIL DRLHACLMSP SLQLSIASPC HGVPCSIGAV EASAIIVSDA PEGLISTLTT
     DHIYYMTVFP AKLALTSEEV