ID   TPPC1_DICDI             Reviewed;         142 AA.
AC   Q557G3; Q86KH6;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Trafficking protein particle complex subunit 1;
GN   Name=trappc1-1; ORFNames=DDB_G0273467;
GN   and
GN   Name=trappc1-2; ORFNames=DDB_G0273579;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: May play a role in vesicular transport from endoplasmic
CC       reticulum to Golgi. {ECO:0000250}.
CC   -!- SUBUNIT: Part of the multisubunit TRAPP (transport protein particle)
CC       complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network {ECO:0000250}.
CC       Endoplasmic reticulum {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAPP small subunits family. BET5 subfamily.
CC       {ECO:0000305}.
CC   -!- CAUTION: The gene for this protein is duplicated in strains AX3 and
CC       AX4. These strains contain a duplication of a segment of 750 kb of
CC       chromosome 2 compared to the corresponding sequence in strain AX2.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000010; EAL70688.1; -; Genomic_DNA.
DR   EMBL; AAFI02000010; EAL70744.1; -; Genomic_DNA.
DR   RefSeq; XP_644579.1; XM_639487.1.
DR   RefSeq; XP_644672.1; XM_639580.1.
DR   AlphaFoldDB; Q557G3; -.
DR   SMR; Q557G3; -.
DR   STRING; 44689.DDB0217147; -.
DR   PaxDb; Q557G3; -.
DR   EnsemblProtists; EAL70688; EAL70688; DDB_G0273467.
DR   EnsemblProtists; EAL70744; EAL70744; DDB_G0273579.
DR   GeneID; 8618944; -.
DR   GeneID; 8619033; -.
DR   KEGG; ddi:DDB_G0273467; -.
DR   KEGG; ddi:DDB_G0273579; -.
DR   dictyBase; DDB_G0273467; trappc1-1.
DR   dictyBase; DDB_G0273579; trappc1-2.
DR   eggNOG; KOG3368; Eukaryota.
DR   HOGENOM; CLU_053380_4_1_1; -.
DR   InParanoid; Q557G3; -.
DR   OMA; HYFETLT; -.
DR   PhylomeDB; Q557G3; -.
DR   Reactome; R-DDI-204005; COPII-mediated vesicle transport.
DR   Reactome; R-DDI-6798695; Neutrophil degranulation.
DR   Reactome; R-DDI-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR   PRO; PR:Q557G3; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030008; C:TRAPP complex; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   InterPro; IPR011012; Longin-like_dom_sf.
DR   InterPro; IPR007233; TRAPPC.
DR   PANTHER; PTHR23249; PTHR23249; 1.
DR   Pfam; PF04099; Sybindin; 1.
DR   SMART; SM01399; Sybindin; 1.
DR   SUPFAM; SSF64356; SSF64356; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus;
KW   Reference proteome; Transport.
FT   CHAIN           1..142
FT                   /note="Trafficking protein particle complex subunit 1"
FT                   /id="PRO_0000330743"
SQ   SEQUENCE   142 AA;  16844 MW;  FE2AD549D5C5F734 CRC64;
     MIYNIYIFNK DGTCIYYEDW NKKKQSQNQS EDQKLLFGML YSLKAFITSS SPKKIDDKTG
     FHCYKTSTYK LHYYETLSCI KFIIMSDPNV PDLRDDLKKI YSQIFVEYVI KNPIYKHGTT
     VKCDTFINQL NLYLKQMPSF SS