ID   TPPC1_RAT               Reviewed;         145 AA.
AC   Q2KMM2;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Trafficking protein particle complex subunit 1;
GN   Name=Trappc1 {ECO:0000312|RGD:1311365};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Brown Norway/Cub, SHR/OlaIpcv, SHRSP, Wistar Hd, and Wistar Kyoto;
RC   TISSUE=Testis;
RA   Liska F., Blachut S., Gosele C., Kren V., Krenova D., Hubner N.;
RT   "Positional cloning of rat hd.";
RL   Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in vesicular transport from endoplasmic
CC       reticulum to Golgi. {ECO:0000250}.
CC   -!- SUBUNIT: Part of the multisubunit transport protein particle (TRAPP)
CC       complex. The heterodimer TRAPPC6B-TRAPPC3 interacts with TRAPPC1 likely
CC       providing a core for TRAPP complex formation.
CC       {ECO:0000250|UniProtKB:Q9Y5R8}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network {ECO:0000250}.
CC       Endoplasmic reticulum {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAPP small subunits family. BET5 subfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY903234; AAX85364.1; -; mRNA.
DR   EMBL; AY903235; AAX85365.1; -; mRNA.
DR   EMBL; AY903236; AAX85366.1; -; mRNA.
DR   EMBL; AY903237; AAX85367.1; -; mRNA.
DR   EMBL; AY903238; AAX85368.1; -; mRNA.
DR   RefSeq; NP_001034467.1; NM_001039378.1.
DR   AlphaFoldDB; Q2KMM2; -.
DR   SMR; Q2KMM2; -.
DR   STRING; 10116.ENSRNOP00000053911; -.
DR   PaxDb; Q2KMM2; -.
DR   PRIDE; Q2KMM2; -.
DR   Ensembl; ENSRNOT00000057079; ENSRNOP00000053911; ENSRNOG00000037627.
DR   GeneID; 287427; -.
DR   KEGG; rno:287427; -.
DR   UCSC; RGD:1311365; rat.
DR   CTD; 58485; -.
DR   RGD; 1311365; Trappc1.
DR   eggNOG; KOG3368; Eukaryota.
DR   GeneTree; ENSGT00940000153761; -.
DR   InParanoid; Q2KMM2; -.
DR   OMA; HYFETPT; -.
DR   OrthoDB; 1431711at2759; -.
DR   PhylomeDB; Q2KMM2; -.
DR   TreeFam; TF323681; -.
DR   Reactome; R-RNO-204005; COPII-mediated vesicle transport.
DR   Reactome; R-RNO-6798695; Neutrophil degranulation.
DR   Reactome; R-RNO-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR   PRO; PR:Q2KMM2; -.
DR   Proteomes; UP000002494; Chromosome 10.
DR   Bgee; ENSRNOG00000037627; Expressed in cerebellum and 20 other tissues.
DR   Genevisible; Q2KMM2; RN.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030008; C:TRAPP complex; ISO:RGD.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   InterPro; IPR011012; Longin-like_dom_sf.
DR   InterPro; IPR007233; TRAPPC.
DR   PANTHER; PTHR23249; PTHR23249; 1.
DR   Pfam; PF04099; Sybindin; 1.
DR   SMART; SM01399; Sybindin; 1.
DR   SUPFAM; SSF64356; SSF64356; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus;
KW   Reference proteome; Transport.
FT   CHAIN           1..145
FT                   /note="Trafficking protein particle complex subunit 1"
FT                   /id="PRO_0000330742"
SQ   SEQUENCE   145 AA;  16882 MW;  7C8C9FCC1118CDC7 CRC64;
     MTVHNLYLFD RNGVCLHYSE WHRKKQAGIP KEEEYKLMYG MLFSIRSFVS KMSPLDMKDG
     FLSFQTSRYK LHYYETPTGI KVVMNTDLGV GPIRDVLHHI YSALYVEFVV KNPLCPLGQT
     VQSELFRSRL DSYVRSLPFF SARAG