ID   TPPC2_DANRE             Reviewed;         140 AA.
AC   Q08CN0;
DT   21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Trafficking protein particle complex subunit 2;
GN   Name=trappc2; ORFNames=zgc:152903;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AB;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in vesicular transport from endoplasmic
CC       reticulum to Golgi. {ECO:0000250}.
CC   -!- SUBUNIT: Part of the multisubunit TRAPP (transport protein particle)
CC       complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, perinuclear region
CC       {ECO:0000250|UniProtKB:P0DI81}. Nucleus {ECO:0000250|UniProtKB:P0DI81}.
CC       Endoplasmic reticulum-Golgi intermediate compartment
CC       {ECO:0000250|UniProtKB:P0DI81}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P0DI81}. Note=Localized in perinuclear granular
CC       structures. {ECO:0000250|UniProtKB:P0DI81}.
CC   -!- SIMILARITY: Belongs to the TRAPP small subunits family. Sedlin
CC       subfamily. {ECO:0000305}.
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DR   EMBL; BC124169; AAI24170.1; -; mRNA.
DR   RefSeq; NP_001307044.1; NM_001320115.1.
DR   AlphaFoldDB; Q08CN0; -.
DR   SMR; Q08CN0; -.
DR   STRING; 7955.ENSDARP00000090467; -.
DR   PaxDb; Q08CN0; -.
DR   Ensembl; ENSDART00000162158; ENSDARP00000137076; ENSDARG00000097660.
DR   Ensembl; ENSDART00000168430; ENSDARP00000136695; ENSDARG00000097660.
DR   GeneID; 767808; -.
DR   KEGG; dre:767808; -.
DR   CTD; 6399; -.
DR   ZFIN; ZDB-GENE-060929-1266; trappc2.
DR   eggNOG; KOG3487; Eukaryota.
DR   GeneTree; ENSGT00940000164277; -.
DR   HOGENOM; CLU_085828_0_2_1; -.
DR   InParanoid; Q08CN0; -.
DR   OrthoDB; 1426075at2759; -.
DR   PhylomeDB; Q08CN0; -.
DR   TreeFam; TF314814; -.
DR   Reactome; R-DRE-204005; COPII-mediated vesicle transport.
DR   Reactome; R-DRE-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR   PRO; PR:Q08CN0; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 9.
DR   Bgee; ENSDARG00000097660; Expressed in muscle tissue and 22 other tissues.
DR   ExpressionAtlas; Q08CN0; baseline.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030008; C:TRAPP complex; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   InterPro; IPR011012; Longin-like_dom_sf.
DR   InterPro; IPR006722; Sedlin.
DR   PANTHER; PTHR12403; PTHR12403; 1.
DR   Pfam; PF04628; Sedlin_N; 1.
DR   SUPFAM; SSF64356; SSF64356; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; ER-Golgi transport; Nucleus; Reference proteome; Transport.
FT   CHAIN           1..140
FT                   /note="Trafficking protein particle complex subunit 2"
FT                   /id="PRO_0000412457"
SQ   SEQUENCE   140 AA;  16454 MW;  D6149ACD963A7954 CRC64;
     MSGSFYFVMV GHHDNPVFEL EFLPPGKAES KDDHRHLNQF IAHAALDLVD ENMWLSNNMY
     LKTVDKFNEW FVSAFVTAGH MRFIMLHDVR QEDGIKNFFN DVYDLYVKFA MNPFYEVNAP
     IRSTAFERKV QFLGKKHLLS