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TPPC2_XENTR
ID   TPPC2_XENTR             Reviewed;         140 AA.
AC   Q28IG8;
DT   21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Trafficking protein particle complex subunit 2;
GN   Name=trappc2; ORFNames=TNeu113o05.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6; TISSUE=Skin;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in vesicular transport from endoplasmic
CC       reticulum to Golgi. {ECO:0000250}.
CC   -!- SUBUNIT: Part of the multisubunit TRAPP (transport protein particle)
CC       complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, perinuclear region
CC       {ECO:0000250|UniProtKB:P0DI81}. Nucleus {ECO:0000250|UniProtKB:P0DI81}.
CC       Endoplasmic reticulum-Golgi intermediate compartment
CC       {ECO:0000250|UniProtKB:P0DI81}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P0DI81}. Note=Localized in perinuclear granular
CC       structures. {ECO:0000250|UniProtKB:P0DI81}.
CC   -!- SIMILARITY: Belongs to the TRAPP small subunits family. Sedlin
CC       subfamily. {ECO:0000305}.
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DR   EMBL; CR760400; CAJ82699.1; -; mRNA.
DR   EMBL; BC121995; AAI21996.1; -; mRNA.
DR   RefSeq; NP_001016642.1; NM_001016642.3.
DR   RefSeq; XP_012812447.1; XM_012956993.2.
DR   AlphaFoldDB; Q28IG8; -.
DR   SMR; Q28IG8; -.
DR   STRING; 8364.ENSXETP00000056766; -.
DR   PaxDb; Q28IG8; -.
DR   DNASU; 549396; -.
DR   GeneID; 549396; -.
DR   KEGG; xtr:549396; -.
DR   CTD; 6399; -.
DR   Xenbase; XB-GENE-965017; trappc2.
DR   eggNOG; KOG3487; Eukaryota.
DR   InParanoid; Q28IG8; -.
DR   OrthoDB; 1426075at2759; -.
DR   Reactome; R-XTR-204005; COPII-mediated vesicle transport.
DR   Reactome; R-XTR-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR   Proteomes; UP000008143; Chromosome 2.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030008; C:TRAPP complex; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   InterPro; IPR011012; Longin-like_dom_sf.
DR   InterPro; IPR006722; Sedlin.
DR   PANTHER; PTHR12403; PTHR12403; 1.
DR   Pfam; PF04628; Sedlin_N; 1.
DR   SUPFAM; SSF64356; SSF64356; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; ER-Golgi transport; Nucleus; Reference proteome; Transport.
FT   CHAIN           1..140
FT                   /note="Trafficking protein particle complex subunit 2"
FT                   /id="PRO_0000412458"
SQ   SEQUENCE   140 AA;  16545 MW;  53888A50A38E4E32 CRC64;
     MSGSFYFVIV GHHDNPVFEM EFLPQGKTES KDDHRHLNQF IAHAALDLVD ENMWLSNNMY
     LKTVDKFNEW FVSAFVTAGH MRFIMLHDVR QEDGIKNFFN EAYDLYIKFA MNPFYEINSP
     LRSTAFDRKI QFLGKKHLLS
 
 
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