TPPC2_XENTR
ID TPPC2_XENTR Reviewed; 140 AA.
AC Q28IG8;
DT 21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Trafficking protein particle complex subunit 2;
GN Name=trappc2; ORFNames=TNeu113o05.1;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Neurula;
RG Sanger Xenopus tropicalis EST/cDNA project;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=N6; TISSUE=Skin;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in vesicular transport from endoplasmic
CC reticulum to Golgi. {ECO:0000250}.
CC -!- SUBUNIT: Part of the multisubunit TRAPP (transport protein particle)
CC complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, perinuclear region
CC {ECO:0000250|UniProtKB:P0DI81}. Nucleus {ECO:0000250|UniProtKB:P0DI81}.
CC Endoplasmic reticulum-Golgi intermediate compartment
CC {ECO:0000250|UniProtKB:P0DI81}. Cytoplasm
CC {ECO:0000250|UniProtKB:P0DI81}. Note=Localized in perinuclear granular
CC structures. {ECO:0000250|UniProtKB:P0DI81}.
CC -!- SIMILARITY: Belongs to the TRAPP small subunits family. Sedlin
CC subfamily. {ECO:0000305}.
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DR EMBL; CR760400; CAJ82699.1; -; mRNA.
DR EMBL; BC121995; AAI21996.1; -; mRNA.
DR RefSeq; NP_001016642.1; NM_001016642.3.
DR RefSeq; XP_012812447.1; XM_012956993.2.
DR AlphaFoldDB; Q28IG8; -.
DR SMR; Q28IG8; -.
DR STRING; 8364.ENSXETP00000056766; -.
DR PaxDb; Q28IG8; -.
DR DNASU; 549396; -.
DR GeneID; 549396; -.
DR KEGG; xtr:549396; -.
DR CTD; 6399; -.
DR Xenbase; XB-GENE-965017; trappc2.
DR eggNOG; KOG3487; Eukaryota.
DR InParanoid; Q28IG8; -.
DR OrthoDB; 1426075at2759; -.
DR Reactome; R-XTR-204005; COPII-mediated vesicle transport.
DR Reactome; R-XTR-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR Proteomes; UP000008143; Chromosome 2.
DR Proteomes; UP000790000; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030008; C:TRAPP complex; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR006722; Sedlin.
DR PANTHER; PTHR12403; PTHR12403; 1.
DR Pfam; PF04628; Sedlin_N; 1.
DR SUPFAM; SSF64356; SSF64356; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; ER-Golgi transport; Nucleus; Reference proteome; Transport.
FT CHAIN 1..140
FT /note="Trafficking protein particle complex subunit 2"
FT /id="PRO_0000412458"
SQ SEQUENCE 140 AA; 16545 MW; 53888A50A38E4E32 CRC64;
MSGSFYFVIV GHHDNPVFEM EFLPQGKTES KDDHRHLNQF IAHAALDLVD ENMWLSNNMY
LKTVDKFNEW FVSAFVTAGH MRFIMLHDVR QEDGIKNFFN EAYDLYIKFA MNPFYEINSP
LRSTAFDRKI QFLGKKHLLS