ID   TPPC3_CAEBR             Reviewed;         181 AA.
AC   Q61IU9; A8XAA6;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Trafficking protein particle complex subunit 3 homolog {ECO:0000250|UniProtKB:O43617};
GN   Name=trpp-3 {ECO:0000312|WormBase:CBG10062};
GN   ORFNames=CBG10062 {ECO:0000312|WormBase:CBG10062};
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: May play a role in vesicular transport from endoplasmic
CC       reticulum to Golgi. Required for the systemic spread of the RNAi
CC       response. {ECO:0000250|UniProtKB:O43617, ECO:0000250|UniProtKB:P34605}.
CC   -!- SUBUNIT: Homodimer. Part of the multisubunit TRAPP (transport protein
CC       particle) complex. {ECO:0000250|UniProtKB:O43617}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network
CC       {ECO:0000250|UniProtKB:Q04183}. Endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:Q9CQP2}.
CC   -!- SIMILARITY: Belongs to the TRAPP small subunits family. BET3 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; HE601459; CAP29574.1; -; Genomic_DNA.
DR   RefSeq; XP_002641725.1; XM_002641679.1.
DR   AlphaFoldDB; Q61IU9; -.
DR   SMR; Q61IU9; -.
DR   STRING; 6238.CBG10062; -.
DR   EnsemblMetazoa; CBG10062.1; CBG10062.1; WBGene00031543.
DR   GeneID; 8583719; -.
DR   KEGG; cbr:CBG_10062; -.
DR   CTD; 8583719; -.
DR   WormBase; CBG10062; CBP02458; WBGene00031543; Cbr-trpp-3.
DR   eggNOG; KOG3330; Eukaryota.
DR   HOGENOM; CLU_087110_0_0_1; -.
DR   InParanoid; Q61IU9; -.
DR   OMA; WTSDNKQ; -.
DR   OrthoDB; 1334804at2759; -.
DR   Proteomes; UP000008549; Chromosome III.
DR   GO; GO:0033106; C:cis-Golgi network membrane; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0030008; C:TRAPP complex; IBA:GO_Central.
DR   GO; GO:0042338; P:cuticle development involved in collagen and cuticulin-based cuticle molting cycle; IEA:EnsemblMetazoa.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:EnsemblMetazoa.
DR   GO; GO:0009306; P:protein secretion; IEA:EnsemblMetazoa.
DR   CDD; cd14942; TRAPPC3_bet3; 1.
DR   InterPro; IPR016721; Bet3.
DR   InterPro; IPR024096; NO_sig/Golgi_transp_ligand-bd.
DR   InterPro; IPR007194; TRAPP_component.
DR   PANTHER; PTHR13048; PTHR13048; 1.
DR   Pfam; PF04051; TRAPP; 1.
DR   PIRSF; PIRSF018293; TRAPP_I_complex_Bet3; 1.
DR   SUPFAM; SSF111126; SSF111126; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Lipoprotein;
KW   Palmitate; Reference proteome; Transport.
FT   CHAIN           1..181
FT                   /note="Trafficking protein particle complex subunit 3
FT                   homolog"
FT                   /id="PRO_0000211576"
FT   LIPID           70
FT                   /note="S-palmitoyl cysteine"
FT                   /evidence="ECO:0000250|UniProtKB:O43617"
SQ   SEQUENCE   181 AA;  19662 MW;  A3450B8AF0862429 CRC64;
     MSKAIKQNLA DSKKMSAELF CLTYGAMVTE MLKDYEDPKD VTVQLDKMGF NMGTRLADDF
     LAKNANVPRC VDTRQIADVL CRNAIPCYLG VSATASSWSS GDREFIITLE SNPLTELVQV
     PPNLVSAGLS YSQMIAGAIR GALEAVHFKV YASAADSGAN TEIRIRFDQV LKDSLPAGED
     D