ID   TPPC4_DICDI             Reviewed;         135 AA.
AC   Q54UU1;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Trafficking protein particle complex subunit 4;
GN   Name=trappc4; ORFNames=DDB_G0280827;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: May play a role in vesicular transport from endoplasmic
CC       reticulum to Golgi. {ECO:0000250|UniProtKB:Q9Y296}.
CC   -!- SUBUNIT: Part of the multisubunit TRAPP (transport protein particle)
CC       complex. {ECO:0000250|UniProtKB:Q9Y296}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000250|UniProtKB:Q9ES56}. Endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:Q9ES56}.
CC   -!- SIMILARITY: Belongs to the TRAPP small subunits family. TRAPPC4
CC       subfamily. {ECO:0000305}.
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DR   EMBL; AAFI02000025; EAL67025.1; -; Genomic_DNA.
DR   RefSeq; XP_641000.1; XM_635908.1.
DR   AlphaFoldDB; Q54UU1; -.
DR   SMR; Q54UU1; -.
DR   STRING; 44689.DDB0252669; -.
DR   PaxDb; Q54UU1; -.
DR   EnsemblProtists; EAL67025; EAL67025; DDB_G0280827.
DR   GeneID; 8621803; -.
DR   KEGG; ddi:DDB_G0280827; -.
DR   dictyBase; DDB_G0280827; trappc4.
DR   eggNOG; KOG3369; Eukaryota.
DR   HOGENOM; CLU_053380_2_2_1; -.
DR   InParanoid; Q54UU1; -.
DR   OMA; YSMEMPI; -.
DR   PhylomeDB; Q54UU1; -.
DR   Reactome; R-DDI-204005; COPII-mediated vesicle transport.
DR   Reactome; R-DDI-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR   PRO; PR:Q54UU1; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030008; C:TRAPP complex; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   InterPro; IPR011012; Longin-like_dom_sf.
DR   InterPro; IPR007233; TRAPPC.
DR   PANTHER; PTHR23249; PTHR23249; 1.
DR   Pfam; PF04099; Sybindin; 1.
DR   SMART; SM01399; Sybindin; 1.
DR   SUPFAM; SSF64356; SSF64356; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane;
KW   Reference proteome; Transport.
FT   CHAIN           1..135
FT                   /note="Trafficking protein particle complex subunit 4"
FT                   /id="PRO_0000330745"
SQ   SEQUENCE   135 AA;  15498 MW;  04733BF50EDCB177 CRC64;
     MTINSIYILN KAGTLIYQND FGNTEKLSHN SYIRLGSTFH SLHAIASNLS PVSGSSSGIE
     VIETEAFKLQ CFQTHTGIKF YVIADPNHQQ LEELLHGVYE LYTDYVLKNP FYEIEMQIRC
     DLFDYKLNRL LGVRE