TPPC5_DICDI
ID TPPC5_DICDI Reviewed; 186 AA.
AC Q54YG5;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=Trafficking protein particle complex subunit 5;
GN Name=trappc5; ORFNames=DDB_G0278643;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- FUNCTION: May play a role in vesicular transport from endoplasmic
CC reticulum to Golgi. {ECO:0000250}.
CC -!- SUBUNIT: Part of the multisubunit TRAPP (transport protein particle)
CC complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network {ECO:0000250}.
CC Endoplasmic reticulum {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TRAPP small subunits family. BET3 subfamily.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAFI02000023; EAL68494.1; -; Genomic_DNA.
DR RefSeq; XP_642237.1; XM_637145.1.
DR AlphaFoldDB; Q54YG5; -.
DR SMR; Q54YG5; -.
DR STRING; 44689.DDB0218079; -.
DR PaxDb; Q54YG5; -.
DR EnsemblProtists; EAL68494; EAL68494; DDB_G0278643.
DR GeneID; 8621446; -.
DR KEGG; ddi:DDB_G0278643; -.
DR dictyBase; DDB_G0278643; trappc5.
DR eggNOG; KOG3315; Eukaryota.
DR HOGENOM; CLU_073154_2_0_1; -.
DR InParanoid; Q54YG5; -.
DR OMA; VPELQNK; -.
DR PhylomeDB; Q54YG5; -.
DR Reactome; R-DDI-204005; COPII-mediated vesicle transport.
DR Reactome; R-DDI-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR PRO; PR:Q54YG5; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:1990070; C:TRAPPI protein complex; IBA:GO_Central.
DR GO; GO:1990071; C:TRAPPII protein complex; IBA:GO_Central.
DR GO; GO:1990072; C:TRAPPIII protein complex; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR CDD; cd14943; TRAPPC5_Trs31; 1.
DR InterPro; IPR024096; NO_sig/Golgi_transp_ligand-bd.
DR InterPro; IPR016696; TRAPP-I_su5.
DR InterPro; IPR007194; TRAPP_component.
DR PANTHER; PTHR20902; PTHR20902; 1.
DR Pfam; PF04051; TRAPP; 1.
DR PIRSF; PIRSF017479; TRAPP_I_complex_Trs31; 1.
DR SUPFAM; SSF111126; SSF111126; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus;
KW Reference proteome; Transport.
FT CHAIN 1..186
FT /note="Trafficking protein particle complex subunit 5"
FT /id="PRO_0000330746"
SQ SEQUENCE 186 AA; 20746 MW; 525538984C8D744B CRC64;
MSKAPVNIVD RPLSKGKGEI NISSFAFLFS EMIQYCQDRI KAGHELEKKL SDMGYSIGPR
LLELLCVREK NSKRETKLLG ILSFIHTTVW KSLFGKPADS LEKSTEADDE YMISDNNMVV
NKFISLPKHL SSLNCAAFVA GIIEGILCSA EFPARVTAHN VAVEGKRFPK TVILIKFNPE
VIERNA