ID   TPPC5_PLAFA             Reviewed;         184 AA.
AC   P15847;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Trafficking protein particle complex subunit 5;
DE   AltName: Full=41-2 protein antigen {ECO:0000303|PubMed:2693962};
GN   Name=TRAPPC5 {ECO:0000305};
OS   Plasmodium falciparum.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=5833;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], SUBCELLULAR LOCATION, AND DEVELOPMENTAL
RP   STAGE.
RC   STRAIN=T9.96 (Thailand);
RX   PubMed=2693962; DOI=10.1016/0166-6851(89)90101-1;
RA   Knapp B., Hundt E., Kuepper H.A.;
RT   "A new blood stage antigen of Plasmodium falciparum transported to the
RT   erythrocyte surface.";
RL   Mol. Biochem. Parasitol. 37:47-56(1989).
CC   -!- FUNCTION: May play a role in vesicular transport from endoplasmic
CC       reticulum to Golgi. {ECO:0000250|UniProtKB:Q03337}.
CC   -!- SUBUNIT: Part of the multisubunit TRAPP (transport protein particle)
CC       complex. {ECO:0000250|UniProtKB:Q03337}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network
CC       {ECO:0000250|UniProtKB:Q03337}. Endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:Q03337}. Cell membrane
CC       {ECO:0000269|PubMed:2693962}; Peripheral membrane protein
CC       {ECO:0000305}. Host membrane {ECO:0000269|PubMed:2693962}; Peripheral
CC       membrane protein {ECO:0000305}. Note=Schizont membrane, internal
CC       surface of parasitized erythrocytes and on membranous structures in the
CC       erythrocyte cytoplasm. {ECO:0000269|PubMed:2693962}.
CC   -!- DEVELOPMENTAL STAGE: Expressed during the parasite blood stage,
CC       specifically in schizonts and free merozoites (at protein level).
CC       {ECO:0000269|PubMed:2693962}.
CC   -!- MISCELLANEOUS: Blood stage antigen transported to the erythrocyte
CC       surface. {ECO:0000269|PubMed:2693962}.
CC   -!- SIMILARITY: Belongs to the TRAPP small subunits family. BET3 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; J04656; AAA29460.1; -; Genomic_DNA.
DR   PIR; A45503; A45503.
DR   AlphaFoldDB; P15847; -.
DR   SMR; P15847; -.
DR   EnsemblProtists; CZU00076; CZU00076; PF3D7_1437800.
DR   VEuPathDB; PlasmoDB:PF3D7_1437800; -.
DR   VEuPathDB; PlasmoDB:Pf7G8-2_000511600; -.
DR   VEuPathDB; PlasmoDB:Pf7G8_140043000; -.
DR   VEuPathDB; PlasmoDB:PfCD01_140043200; -.
DR   VEuPathDB; PlasmoDB:PfDd2_140042200; -.
DR   VEuPathDB; PlasmoDB:PfGA01_140043300; -.
DR   VEuPathDB; PlasmoDB:PfGB4_140043900; -.
DR   VEuPathDB; PlasmoDB:PfGN01_140043100; -.
DR   VEuPathDB; PlasmoDB:PfHB3_140043500; -.
DR   VEuPathDB; PlasmoDB:PfIT_140044200; -.
DR   VEuPathDB; PlasmoDB:PfKE01_140042700; -.
DR   VEuPathDB; PlasmoDB:PfKH01_140043300; -.
DR   VEuPathDB; PlasmoDB:PfKH02_140043500; -.
DR   VEuPathDB; PlasmoDB:PfML01_140043300; -.
DR   VEuPathDB; PlasmoDB:PfNF135_140042000; -.
DR   VEuPathDB; PlasmoDB:PfNF166_140040700; -.
DR   VEuPathDB; PlasmoDB:PfNF54_140041600; -.
DR   VEuPathDB; PlasmoDB:PfSD01_140041100; -.
DR   VEuPathDB; PlasmoDB:PfSN01_140045000; -.
DR   VEuPathDB; PlasmoDB:PfTG01_140043100; -.
DR   OMA; VPELQNK; -.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030008; C:TRAPP complex; IEA:InterPro.
DR   GO; GO:0048193; P:Golgi vesicle transport; IEA:InterPro.
DR   CDD; cd14943; TRAPPC5_Trs31; 1.
DR   InterPro; IPR024096; NO_sig/Golgi_transp_ligand-bd.
DR   InterPro; IPR016696; TRAPP-I_su5.
DR   InterPro; IPR007194; TRAPP_component.
DR   PANTHER; PTHR20902; PTHR20902; 1.
DR   Pfam; PF04051; TRAPP; 1.
DR   PIRSF; PIRSF017479; TRAPP_I_complex_Trs31; 1.
DR   SUPFAM; SSF111126; SSF111126; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus;
KW   Host membrane; Malaria; Membrane; Transport.
FT   CHAIN           1..184
FT                   /note="Trafficking protein particle complex subunit 5"
FT                   /id="PRO_0000211582"
SQ   SEQUENCE   184 AA;  21512 MW;  DB16CD15E8355963 CRC64;
     MDKSKSSIEK ELNRIKQDVS LSAFSILFSE MVQYCLYKSK RGYRIEDCLH EMGLRVGYKL
     NEYLTYKNKV KRSINIINIL TFISKHVWKY LFQHSSDLLK SQDSIYEYMI CDKNILLNKF
     INVPKDYGNI NCAAFAAGIV EGFLCSSEFQ ADVTAHTIHE GDDNYNTTIF IKFYPEVVER
     EKNH