ID   TPRA1_CAEBR             Reviewed;         454 AA.
AC   Q60QP4; A8Y0M1;
DT   10-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   10-JAN-2006, sequence version 2.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Transmembrane protein adipocyte-associated 1 homolog;
GN   Name=tpra-1; ORFNames=CBG21730;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0359 family. {ECO:0000305}.
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DR   EMBL; HE600966; CAP38440.2; -; Genomic_DNA.
DR   AlphaFoldDB; Q60QP4; -.
DR   STRING; 6238.CBG21730; -.
DR   PRIDE; Q60QP4; -.
DR   EnsemblMetazoa; CBG21730.1; CBG21730.1; WBGene00040430.
DR   WormBase; CBG21730; CBP27932; WBGene00040430; Cbr-tpra-1.
DR   eggNOG; KOG4536; Eukaryota.
DR   HOGENOM; CLU_702556_0_0_1; -.
DR   InParanoid; Q60QP4; -.
DR   OMA; FRIRYWD; -.
DR   OrthoDB; 609919at2759; -.
DR   Proteomes; UP000008549; Chromosome IV.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IBA:GO_Central.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   InterPro; IPR018781; TPRA1/CAND2/CAND8.
DR   PANTHER; PTHR15876; PTHR15876; 1.
DR   Pfam; PF10160; Tmemb_40; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..454
FT                   /note="Transmembrane protein adipocyte-associated 1
FT                   homolog"
FT                   /id="PRO_0000076104"
FT   TRANSMEM        80..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        151..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        262..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        290..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          408..454
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        422..436
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        26
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        44
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        258
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        322
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        323
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   454 AA;  51360 MW;  9F5470C3EB581980 CRC64;
     MSVIFHENPG TSLGSVVSSD TNPSFNHTLS IETSPEWIDD LFSNVSFIDS TTHQVIRGFC
     RDVFVYRLPG GFRIRYWDAA ILIPNLLFLL FLFLKCTSVI RKLQTGNSPV LRAFTLLVYV
     STLVNIIRCV YSMTLSMTDG IEQTVDQTLW IIIKFFYLTA EFCALTFGLL FGHLDNGRSI
     LIALLGTLLV SIPHTAVQVI VEMKIIDNSW LPLTYFDIES DGGFVFWVLS SATLALVYFF
     IMCLPLVCCQ KYTKLPSNGS FFIYCMMMVT LNILQSMGAA LILFKSSDGL CFVGVSTYVY
     FVLYPPIIYF TFLRRKLKTP PNNTSGLFMY RKHKDEQGSG DLPDSYYPRF SGLTSPSYDD
     LFDYDRDARF THYDISTNEY VQHPHYNTYS TPLIMSTVET AESTVTTRTG SDDFAHHRDS
     MLSEPSTGTT TRHLKGLGPQ GSLVFEEDPS SLRL