ID   TPT_FLATR               Reviewed;         407 AA.
AC   P49132;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Triose phosphate/phosphate translocator, chloroplastic;
DE            Short=cTPT;
DE   Flags: Precursor;
GN   Name=TPT;
OS   Flaveria trinervia (Clustered yellowtops) (Oedera trinervia).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC   Heliantheae alliance; Tageteae; Flaveria.
OX   NCBI_TaxID=4227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Leaf;
RX   PubMed=8148878; DOI=10.1046/j.1365-313x.1994.05020215.x;
RA   Fischer K., Arbinger B., Kammerer B., Busch C., Brink S., Wallmeier H.,
RA   Sauer N., Eckerskorn C., Fluegge U.-I.;
RT   "Cloning and in vivo expression of functional triose phosphate/phosphate
RT   translocators from C3- and C4-plants: evidence for the putative
RT   participation of specific amino acid residues in the recognition of
RT   phosphoenolpyruvate.";
RL   Plant J. 5:215-226(1994).
CC   -!- FUNCTION: Mediates the export of fixed carbons from the chloroplasts
CC       into the cytosol in the form of triose phosphates. In addition, it can
CC       also bind and transport phosphoenolpyruvate, thereby increasing the
CC       photosynthetic efficiency of C4-plants.
CC   -!- SUBUNIT: Homodimer.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane; Multi-pass
CC       membrane protein. Note=Located in zones of contact between the inner
CC       and outer membrane of the chloroplast.
CC   -!- SIMILARITY: Belongs to the TPT transporter family. TPT (TC 2.A.7.9)
CC       subfamily. {ECO:0000305}.
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DR   EMBL; Z26632; CAA81385.1; -; mRNA.
DR   PIR; S37550; S37550.
DR   AlphaFoldDB; P49132; -.
DR   SMR; P49132; -.
DR   GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015605; F:organophosphate ester transmembrane transporter activity; IEA:UniProt.
DR   GO; GO:0015120; F:phosphoglycerate transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR004853; Sugar_P_trans_dom.
DR   InterPro; IPR004696; Tpt_PEP_transl.
DR   Pfam; PF03151; TPT; 1.
DR   TIGRFAMs; TIGR00817; tpt; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Membrane; Plastid; Transit peptide; Transmembrane;
KW   Transmembrane helix; Transport.
FT   TRANSIT         1..81
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           82..407
FT                   /note="Triose phosphate/phosphate translocator,
FT                   chloroplastic"
FT                   /id="PRO_0000035706"
FT   TOPO_DOM        82..101
FT                   /note="Chloroplast intermembrane"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        123..134
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        156..212
FT                   /note="Chloroplast intermembrane"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        234..277
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        278..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        298..375
FT                   /note="Chloroplast intermembrane"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        376..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        397..407
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   SITE            222
FT                   /note="May be essential for binding and transport of
FT                   phosphoenolpyruvate"
SQ   SEQUENCE   407 AA;  44345 MW;  3907FD4E8028C876 CRC64;
     MESRVLSSGA TAISGVPRLT KPAGRITTTT VAVAFPARLN ATGGNVVWGR QLRPSLLNLD
     HSSPVSLVTK PVKRDVLKPC SATASDSAGD AAPVGFLAKY PFLVTGFFFF MWYFLNVIFN
     ILNKKIYNYF PYPYFVSVIH LAVGVVYCLG SWTVGLPKRA PVDSNILKLL IPVGFCHALG
     HVTSNVSFAA VAVSFTHTIK ALEPFFNAAA SQFVLGQSIP ISLWLSLAPV VIGVSMASLT
     ELSFNWLGFI SAMISNISFT YRSIYSKKAM TDMDSTNLYA YISIIALLFC IPPAVLFEGP
     QLLKHGFNDA IAKVGMIKFI SDLFWVGMFY HLYNQIATNT LERVAPLTHA VGNVLKRVFV
     IGFSIIVFGN KISTQTAIGT SIAIAGVAIY SLIKARIEEE KRRMKSA