ID   TR05_CURCL              Reviewed;         398 AA.
AC   A0A348AXX8;
DT   12-AUG-2020, integrated into UniProtKB/Swiss-Prot.
DT   07-NOV-2018, sequence version 1.
DT   25-MAY-2022, entry version 12.
DE   RecName: Full=Transcription factor kkR {ECO:0000303|PubMed:29686660};
DE   AltName: Full=KK-1 biosynthesis cluster regulator {ECO:0000303|PubMed:29686660};
GN   Name=kkR {ECO:0000303|PubMed:29686660};
GN   Synonyms=TR05 {ECO:0000303|PubMed:29686660}; ORFNames=TRAF068005;
OS   Curvularia clavata.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Curvularia.
OX   NCBI_TaxID=95742;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND PATHWAY.
RC   STRAIN=BAUA-2787;
RX   PubMed=29686660; DOI=10.3389/fmicb.2018.00690;
RA   Yoshimi A., Yamaguchi S., Fujioka T., Kawai K., Gomi K., Machida M.,
RA   Abe K.;
RT   "Heterologous Production of a Novel Cyclic Peptide Compound, KK-1, in
RT   Aspergillus oryzae.";
RL   Front. Microbiol. 9:690-690(2018).
CC   -!- FUNCTION: Transcription factor that positively regulates the expression
CC       of the gene clusters that mediate the biosynthesis of KK-1, a novel
CC       cyclic decapeptide compound with potent antifungal activity.
CC       {ECO:0000269|PubMed:29686660}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LC371755; BBC83961.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A348AXX8; -.
DR   SMR; A0A348AXX8; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   DNA-binding; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..398
FT                   /note="Transcription factor kkR"
FT                   /id="PRO_0000450432"
FT   DOMAIN          31..62
FT                   /note="bZIP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          34..50
FT                   /note="Basic motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          51..58
FT                   /note="Leucine-zipper"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
SQ   SEQUENCE   398 AA;  44454 MW;  68FBEB4111CFF855 CRC64;
     MTFVETVAVP DNEERPSAGH NRPVADSTKC PNAREMKVQN RVAQRTHHRR LKTKLEVLRE
     RLKEPEKQVG EPARVQTSTS TLVSDAATSL ADSMCLVPAV QNDQAMAFDF LMTPSPSVGN
     DCPSNDLETM RQAASVHSNT LGGAFPLNRS PCTENMTPES QVSLSTAPLC FTSVVPAELD
     MDAFCTLDSS DWSRPNEESL LRLANYSTSV SPTNVQWGVD ENAPLQDRVR YMRDQAVAMG
     FGSLDDVVEA HYTQKLECTS PSFQEQRLSR NRRLSRLLST LHNAAKDWSE WERRGLQEQV
     TQGAEDILVS ELNSYITQRS MNSTDDKIIT GGLLDEQSRL RQDVEERRRL QDSLPNLGAL
     LTTLLSRSNA PNQDARRDTV LAMIKTMCFD QDENMSIS