ID   TR102_RAT               Reviewed;         327 AA.
AC   Q675C0;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Taste receptor type 2 member 102;
DE            Short=T2R102;
DE   AltName: Full=Taste receptor type 2 member 37;
DE            Short=T2R37;
GN   Name=Tas2r102 {ECO:0000312|RGD:1564838}; Synonyms=Tas2r37;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1] {ECO:0000312|EMBL:AAS57908.1}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Sprague-Dawley {ECO:0000312|EMBL:AAS57908.1};
RA   Conte C., Ebeling M., Marcuz A., Andres-Barquin P.J.;
RT   "Identification of new putative rat taste receptors belonging to the T2R
RT   family.";
RL   Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Putative taste receptor which may play a role in the
CC       perception of bitterness. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- MISCELLANEOUS: Several bitter taste receptors are expressed in a single
CC       taste receptor cell. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor T2R family.
CC       {ECO:0000255}.
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DR   EMBL; AY486337; AAS57908.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q675C0; -.
DR   SMR; Q675C0; -.
DR   STRING; 10116.ENSRNOP00000048055; -.
DR   GlyGen; Q675C0; 2 sites.
DR   PaxDb; Q675C0; -.
DR   Ensembl; ENSRNOT00000050359; ENSRNOP00000048055; ENSRNOG00000030993.
DR   UCSC; RGD:1564838; rat.
DR   RGD; 1564838; Tas2r102.
DR   eggNOG; ENOG502TE6X; Eukaryota.
DR   InParanoid; Q675C0; -.
DR   PhylomeDB; Q675C0; -.
DR   TreeFam; TF335891; -.
DR   PRO; PR:Q675C0; -.
DR   Proteomes; UP000002494; Chromosome 4.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0033038; F:bitter taste receptor activity; IBA:GO_Central.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IBA:GO_Central.
DR   InterPro; IPR007960; TAS2R.
DR   Pfam; PF05296; TAS2R; 1.
PE   3: Inferred from homology;
KW   G-protein coupled receptor; Glycoprotein; Membrane; Receptor;
KW   Reference proteome; Sensory transduction; Taste; Transducer; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..327
FT                   /note="Taste receptor type 2 member 102"
FT                   /id="PRO_0000248247"
FT   TOPO_DOM        1..7
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        8..28
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        29..46
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        68..87
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        88..108
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        109..124
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        125..145
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        146..179
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..200
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        201..229
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        230..250
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        251..260
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        261..281
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        282..327
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        159
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        179
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   327 AA;  37656 MW;  0DD60A2B67DD121A CRC64;
     MEPVIYSFAT LLIHVEFIFG NLSNGFIVLS NFWDWVIKRK LSTIDKILLT LAISRITLIW
     EIYTWFTSVY GPSSFAIGMK LQILYFTWIL SSHFSLWFAT ALSIFYLLRI ANCSWKIFLY
     LKWRLKQVIV GMLLASLVFL PGILTQRTLE ERPYRYGGNT SEDSMETDFA RFTELILFNL
     TIFSVIPFSL ASISFLLLIF SLWKHLRKMQ LSSRGHGDPS TKAHTNALRI MVSFLLLYSI
     YFLSLLLSWI AQKHHSKLVD IIGIITGLMY PSAHSFILIL GNSKLMQTSL WILSHLRCRL
     KGENILNPSG NQVTSCYIFC IANKSVS