ID   TR112_CAEEL             Reviewed;         125 AA.
AC   O45241;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Multifunctional methyltransferase subunit TRM112-like protein;
DE   AltName: Full=tRNA methyltransferase 112 homolog;
GN   ORFNames=C04H5.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Acts as an activator of both RNA and protein
CC       methyltransferases. {ECO:0000250|UniProtKB:Q9UI30}.
CC   -!- SIMILARITY: Belongs to the TRM112 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Z81462; CAB03840.1; -; Genomic_DNA.
DR   PIR; T18929; T18929.
DR   RefSeq; NP_497021.1; NM_064620.1.
DR   AlphaFoldDB; O45241; -.
DR   SMR; O45241; -.
DR   BioGRID; 47099; 3.
DR   DIP; DIP-26016N; -.
DR   STRING; 6239.C04H5.1; -.
DR   EPD; O45241; -.
DR   PaxDb; O45241; -.
DR   PeptideAtlas; O45241; -.
DR   EnsemblMetazoa; C04H5.1.1; C04H5.1.1; WBGene00007312.
DR   UCSC; C04H5.1; c. elegans.
DR   WormBase; C04H5.1; CE15587; WBGene00007312; -.
DR   eggNOG; KOG1088; Eukaryota.
DR   GeneTree; ENSGT00940000164608; -.
DR   HOGENOM; CLU_086140_2_0_1; -.
DR   InParanoid; O45241; -.
DR   OMA; NMLTSKC; -.
DR   OrthoDB; 1465773at2759; -.
DR   PhylomeDB; O45241; -.
DR   Reactome; R-CEL-156581; Methylation.
DR   Reactome; R-CEL-72764; Eukaryotic Translation Termination.
DR   PRO; PR:O45241; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00007312; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0018364; P:peptidyl-glutamine methylation; IBA:GO_Central.
DR   GO; GO:0070476; P:rRNA (guanine-N7)-methylation; IBA:GO_Central.
DR   GO; GO:0030488; P:tRNA methylation; IBA:GO_Central.
DR   InterPro; IPR039127; Trm112.
DR   InterPro; IPR005651; Trm112-like.
DR   PANTHER; PTHR12773; PTHR12773; 1.
DR   Pfam; PF03966; Trm112p; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..125
FT                   /note="Multifunctional methyltransferase subunit TRM112-
FT                   like protein"
FT                   /id="PRO_0000215799"
FT   DOMAIN          2..121
FT                   /note="TRM112"
SQ   SEQUENCE   125 AA;  14572 MW;  995F62EC2DC083E7 CRC64;
     MKLFVHNFMS SRFLKNVTVG YPLNLVVKQF VEKDIEFDRD NTIVMLDRIQ YEALIVAAAA
     VNQSDRIPRE KPEKWDELTD EQLRVFHHLL MNIDVIDGEL ICPETKTVFP IRDGIPNMLK
     VDAEK