ID   TR3N_HUMAN              Reviewed;         133 AA.
AC   Q6F5E7;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Putative uncharacterized protein TXNRD3NB {ECO:0000305};
DE   AltName: Full=Thioredoxin reductase 2 intronic transcript 1;
DE   AltName: Full=Thioredoxin reductase 3 intronic transcript 1;
DE   AltName: Full=Thioredoxin reductase 3 neighbor gene protein;
DE            Short=TXNRD3 neighbor gene protein;
DE   AltName: Full=Thioredoxin reductase 3 new transcript 1;
GN   Name=TXNRD3NB; Synonyms=TR2IT1, TXNRD3IT1, TXNRD3NT1;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RX   PubMed=15674732; DOI=10.1007/s00335-004-2416-y;
RA   Matsuzaka Y., Okamoto K., Mabuchi T., Iizuka M., Ozawa A., Oka A.,
RA   Tamiya G., Kulski J.K., Inoko H.;
RT   "Identification and characterization of novel variants of the thioredoxin
RT   reductase 3 new transcript 1 TXNRD3NT1.";
RL   Mamm. Genome 16:41-49(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   IDENTIFICATION.
RX   PubMed=33023362; DOI=10.1080/14789450.2020.1833722;
RA   Gupta N., Sahar T., Khullar D., Jain S.K., Wajid S.;
RT   "Differential expression of MAP3K7 and TROPONIN C proteins and related
RT   perturbations in renal amyloidosis.";
RL   Expert Rev. Proteomics 17:685-694(2020).
CC   -!- INTERACTION:
CC       Q6F5E7; Q8N2N9-4: ANKRD36B; NbExp=3; IntAct=EBI-18122152, EBI-12170453;
CC       Q6F5E7; Q9Y3E2: BOLA1; NbExp=3; IntAct=EBI-18122152, EBI-1049556;
CC       Q6F5E7; A0A087WZT3: BOLA2B; NbExp=3; IntAct=EBI-18122152, EBI-12006120;
CC       Q6F5E7; Q9BW66: CINP; NbExp=3; IntAct=EBI-18122152, EBI-739784;
CC       Q6F5E7; Q9UI47-2: CTNNA3; NbExp=3; IntAct=EBI-18122152, EBI-11962928;
CC       Q6F5E7; Q14192: FHL2; NbExp=3; IntAct=EBI-18122152, EBI-701903;
CC       Q6F5E7; Q8N7B6-2: PACRGL; NbExp=3; IntAct=EBI-18122152, EBI-10694433;
CC       Q6F5E7; O95721: SNAP29; NbExp=3; IntAct=EBI-18122152, EBI-490676;
CC   -!- TISSUE SPECIFICITY: Expressed in pancreas, esophagus, bone marrow and
CC       keratinocytes. {ECO:0000269|PubMed:15674732}.
CC   -!- CAUTION: Product of a dubious CDS prediction. {ECO:0000305}.
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DR   EMBL; AB113648; BAD26752.1; -; mRNA.
DR   EMBL; BC130546; AAI30547.1; -; mRNA.
DR   EMBL; BC130548; AAI30549.1; -; mRNA.
DR   RefSeq; NP_001034872.1; NM_001039783.1.
DR   AlphaFoldDB; Q6F5E7; -.
DR   BioGRID; 570785; 19.
DR   IntAct; Q6F5E7; 10.
DR   STRING; 9606.ENSP00000373066; -.
DR   BioMuta; TXNRD3NB; -.
DR   PaxDb; Q6F5E7; -.
DR   PRIDE; Q6F5E7; -.
DR   ProteomicsDB; 66289; -.
DR   DNASU; 645840; -.
DR   UCSC; uc003ejc.4; human.
DR   neXtProt; NX_Q6F5E7; -.
DR   eggNOG; ENOG502TED4; Eukaryota.
DR   HOGENOM; CLU_1997862_0_0_1; -.
DR   InParanoid; Q6F5E7; -.
DR   OrthoDB; 1377092at2759; -.
DR   PathwayCommons; Q6F5E7; -.
DR   SignaLink; Q6F5E7; -.
DR   BioGRID-ORCS; 645840; 12 hits in 1076 CRISPR screens.
DR   GenomeRNAi; 645840; -.
DR   Pharos; Q6F5E7; Tdark.
DR   PRO; PR:Q6F5E7; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q6F5E7; protein.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..133
FT                   /note="Putative uncharacterized protein TXNRD3NB"
FT                   /id="PRO_0000340667"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          82..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   133 AA;  14331 MW;  337721F08CEA3BDC CRC64;
     MRDLSERRLG QPELKAEQQM PLEPVRARLS VGLACCCSHT TAEASSLEHG DKVFGQGFPS
     PLEEIKRLLK ISRALQARSV PSTQEKAKCL SGEPGQPEGK GQETYPGPGK VEGKAEPAMR
     KDDVCPGMKC ISG