ID   TR852_SCHPO             Reviewed;         618 AA.
AC   O74748;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Transport protein particle subunit trs85-2;
DE            Short=TRAPP subunit trs85-2;
GN   Name=trs85-2; ORFNames=SPBC1734.07c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Component of the TRAPP I and TRAPP II complexes. TRAPP I
CC       plays a key role in the late stages of endoplasmic reticulum to Golgi
CC       traffic. TRAPP II seems to play a role in intra-Golgi transport. Has a
CC       role late in meiosis following DNA replication (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Part of the multisubunit TRAPP (transport protein particle)
CC       complexes I and II.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRS85 family. {ECO:0000305}.
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DR   EMBL; CU329671; CAA21301.1; -; Genomic_DNA.
DR   PIR; T39654; T39654.
DR   RefSeq; NP_595424.1; NM_001021332.2.
DR   AlphaFoldDB; O74748; -.
DR   SMR; O74748; -.
DR   BioGRID; 276422; 25.
DR   STRING; 4896.SPBC1734.07c.1; -.
DR   iPTMnet; O74748; -.
DR   MaxQB; O74748; -.
DR   PaxDb; O74748; -.
DR   PRIDE; O74748; -.
DR   EnsemblFungi; SPBC1734.07c.1; SPBC1734.07c.1:pep; SPBC1734.07c.
DR   PomBase; SPBC1734.07c; -.
DR   VEuPathDB; FungiDB:SPBC1734.07c; -.
DR   eggNOG; KOG1938; Eukaryota.
DR   HOGENOM; CLU_014185_0_0_1; -.
DR   InParanoid; O74748; -.
DR   OMA; PHETFAH; -.
DR   PhylomeDB; O74748; -.
DR   Reactome; R-SPO-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR   PRO; PR:O74748; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0000407; C:phagophore assembly site; IBA:GO_Central.
DR   GO; GO:1990072; C:TRAPPIII protein complex; ISO:PomBase.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0006886; P:intracellular protein transport; ISO:PomBase.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0034497; P:protein localization to phagophore assembly site; IBA:GO_Central.
DR   InterPro; IPR024420; TRAPP_III_complex_Trs85.
DR   PANTHER; PTHR12975; PTHR12975; 1.
DR   Pfam; PF12739; TRAPPC-Trs85; 1.
PE   3: Inferred from homology;
KW   ER-Golgi transport; Golgi apparatus; Meiosis; Reference proteome;
KW   Transport.
FT   CHAIN           1..618
FT                   /note="Transport protein particle subunit trs85-2"
FT                   /id="PRO_0000343162"
SQ   SEQUENCE   618 AA;  70597 MW;  9E7E35FF547F0775 CRC64;
     MESNLSAKGI FQHASANASG ELFQEPVTED LEKVMQSKGL YSMEELCSII QEAYAPRVSV
     LCSRDADEFA MRKGYPKGFW ELLYPFGDRI RGKVNRRGMN GEMLTLENLN LHFVPIDALE
     SHLSEASFPS LRSVLCERYP GLVSPEPPSD YSFGVHYKNV ERWAWTLAHE GNYQMPLPVY
     VRQLLTGIPI TPFETFSHPV AHLVVVTSHN PSPFESLRSL INSIPYLSLP AFVFNDINYL
     FVYVHDEDQH DLELSMAIFD TMKQTFGDCG YFLRLHSQKA TLDYEHTVPF PTSSWLSAEE
     RLHLLSNTDT EIRLLFESDN ESLRRLSSHI AFNGIVSYLD KCVRAWDDQY ASPRRGITGK
     LLFASRKYLS SSNASTNSNY FPSSNAYRPF SPEAYLRKLA DYSFMLRDYS HANQIYEIAS
     RQYENDGACL YSAASLEMIV ITEHILHLKM PYMSLTNTLR INEYMQSAML NYLNKSFNSY
     YHAARCFLLL GQFLSCLPAP KVDDAANWNA GLLYSKRLGP VGRAMIFQQT HTLFKSLSYL
     KTESTDPFSN KRTRKAALWC VLTADAWLRC RIPFRAKPFV EEAKLFYGKI DWKDLKECVA
     ALDEVEVSKQ PASNIPSS