ID   TRA1_MYCTU              Reviewed;         415 AA.
AC   P60230; L0T7K9; P35882;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-JAN-2004, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Transposase for insertion sequence element IS1081;
GN   OrderedLocusNames=Rv1199c; ORFNames=MTCI364.11c;
GN   and
GN   OrderedLocusNames=Rv2512c; ORFNames=MTCY07A7.18c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- FUNCTION: Required for the transposition of the insertion element.
CC   -!- SIMILARITY: Belongs to the transposase mutator family. {ECO:0000305}.
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DR   EMBL; AL123456; CCP43955.1; -; Genomic_DNA.
DR   EMBL; AL123456; CCP45306.1; -; Genomic_DNA.
DR   RefSeq; NP_215715.1; NC_000962.3.
DR   RefSeq; NP_217028.1; NC_000962.3.
DR   RefSeq; WP_003904572.1; NZ_KK339370.1.
DR   AlphaFoldDB; P60230; -.
DR   SMR; P60230; -.
DR   PaxDb; P60230; -.
DR   DNASU; 23492655; -.
DR   DNASU; 886092; -.
DR   DNASU; 888515; -.
DR   GeneID; 45425170; -.
DR   GeneID; 886092; -.
DR   GeneID; 888515; -.
DR   KEGG; mtu:Rv1199c; -.
DR   KEGG; mtu:Rv2512c; -.
DR   TubercuList; Rv1199c; -.
DR   TubercuList; Rv2512c; -.
DR   eggNOG; COG3328; Bacteria.
DR   InParanoid; P60230; -.
DR   OMA; IHAQEDK; -.
DR   PhylomeDB; P60230; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR   InterPro; IPR001207; Transposase_mutator.
DR   PANTHER; PTHR33217; PTHR33217; 1.
DR   Pfam; PF00872; Transposase_mut; 1.
DR   PROSITE; PS01007; TRANSPOSASE_MUTATOR; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Reference proteome; Transposable element;
KW   Transposition.
FT   CHAIN           1..415
FT                   /note="Transposase for insertion sequence element IS1081"
FT                   /id="PRO_0000211350"
SQ   SEQUENCE   415 AA;  45810 MW;  23E187DC0A06A774 CRC64;
     MTSSHLIDTE QLLADQLAQA SPDLLRGLLS TFIAALMGAE ADALCGAGYR ERSDERSNQR
     NGYRHRDFDT RAATIDVAIP KLRQGSYFPD WLLQRRKRAE RALTSVVATC YLLGVSTRRM
     ERLVETLGVT KLSKSQVSIM AKELDEAVEA FRTRPLDAGP YTFLAADALV LKVREAGRVV
     GVHTLIATGV NAEGYREILG IQVTSAEDGA GWLAFFRDLV ARGLSGVALV TSDAHAGLVA
     AIGATLPAAA WQRCRTHYAA NLMAATPKPS WPWVRTLLHS IYDQPDAESV VAQYDRVLDA
     LTDKLPAVAE HLDTARTDLL AFTAFPKQIW RQIWSNNPQE RLNREVRRRT DVVGIFPDRA
     SIIRLVGAVL AEQHDEWIEG RRYLGLEVLT RARAALTSTE EPAKQQTTNT PALTT