ID   TRA4_BACFG              Reviewed;         326 AA.
AC   P37247;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Transposase for insertion sequence element IS4351;
DE   AltName: Full=Transposon TN4551;
OS   Bacteroides fragilis.
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=817;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2820936; DOI=10.1128/jb.169.10.4589-4596.1987;
RA   Smith C.J.;
RT   "Nucleotide sequence analysis of Tn4551: use of ermFS operon fusions to
RT   detect promoter activity in Bacteroides fragilis.";
RL   J. Bacteriol. 169:4589-4596(1987).
CC   -!- FUNCTION: Required for the transposition of the insertion element.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the transposase IS30 family. {ECO:0000305}.
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DR   EMBL; M17808; AAA27430.1; -; Genomic_DNA.
DR   RefSeq; WP_005794072.1; NZ_VOHY01000019.1.
DR   AlphaFoldDB; P37247; -.
DR   PRIDE; P37247; -.
DR   GeneID; 61622110; -.
DR   GeneID; 66292346; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR001598; Transposase_IS30_CS.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
DR   PROSITE; PS01043; TRANSPOSASE_IS30; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Plasmid; Transposable element;
KW   Transposition.
FT   CHAIN           1..326
FT                   /note="Transposase for insertion sequence element IS4351"
FT                   /id="PRO_0000211895"
FT   DOMAIN          156..317
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00457"
SQ   SEQUENCE   326 AA;  37994 MW;  CEE28AC9D662112D CRC64;
     MSKHITEEQR YAISMMLQIP MSKKAIAEAI GVDKSTVYRE IKRNCDARSG SYSMELAQRK
     ADRRKQQKHR KEVLTPAMRK RIIKLLKKGF SPEQIVGRSR LEGIAMVSHE TIYRWIWEDK
     RRGGKLHKYL RRQGRRYAKR GSKNAGRGFI PGRVDIDERP EIVELKERFG DLEIDTIIGK
     NHKGAILTIN DRATSRVWIR KLSGKEAIPV AKIAVWALRK VKNLIHTITA DNGKEFAKHE
     EIAQKLEIKF YFCKPYHSWE RGANENTNGL IRQYIPKGKD FSEVTNKQIK WIENKLNNRP
     RKRLGYLTPN EKFKQIINQN SVAFAS