ID   TRA6_ENTFA              Reviewed;         390 AA.
AC   P59787;
DT   25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2003, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Transposase for insertion sequence element IS256 in transposon Tn4001;
GN   OrderedLocusNames=EF_0125;
GN   and
GN   OrderedLocusNames=EF_0529;
GN   and
GN   OrderedLocusNames=EF_2187;
GN   and
GN   OrderedLocusNames=EF_2632;
GN   and
GN   OrderedLocusNames=EF_3100;
GN   and
GN   OrderedLocusNames=EF_3215;
GN   and
GN   OrderedLocusNames=EF_A0059;
GN   and
GN   OrderedLocusNames=EF_A0062;
GN   and
GN   OrderedLocusNames=EF_B0052;
GN   and
GN   OrderedLocusNames=EF_C0004;
OS   Enterococcus faecalis (strain ATCC 700802 / V583).
OG   Plasmid pTEF1, Plasmid pTEF2, and Plasmid pTEF3.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=226185;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700802 / V583;
RX   PubMed=12663927; DOI=10.1126/science.1080613;
RA   Paulsen I.T., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R.,
RA   Read T.D., Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA   Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C.,
RA   DeBoy R.T., Durkin S.A., Kolonay J.F., Madupu R., Nelson W.C.,
RA   Vamathevan J.J., Tran B., Upton J., Hansen T., Shetty J., Khouri H.M.,
RA   Utterback T.R., Radune D., Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT   "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT   faecalis.";
RL   Science 299:2071-2074(2003).
CC   -!- FUNCTION: Required for the transposition of the insertion element.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the transposase mutator family. {ECO:0000305}.
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DR   EMBL; AE016830; AAO80000.1; -; Genomic_DNA.
DR   EMBL; AE016830; AAO80376.1; -; Genomic_DNA.
DR   EMBL; AE016830; AAO81919.1; -; Genomic_DNA.
DR   EMBL; AE016830; AAO82341.1; -; Genomic_DNA.
DR   EMBL; AE016830; AAO82780.1; -; Genomic_DNA.
DR   EMBL; AE016830; AAO82887.1; -; Genomic_DNA.
DR   EMBL; AE016833; AAO83053.1; -; Genomic_DNA.
DR   EMBL; AE016833; AAO83056.1; -; Genomic_DNA.
DR   EMBL; AE016831; AAO83141.1; -; Genomic_DNA.
DR   EMBL; AE016832; AAO83077.1; -; Genomic_DNA.
DR   RefSeq; NP_813928.1; NC_004668.1.
DR   RefSeq; NP_814305.1; NC_004668.1.
DR   RefSeq; NP_815849.1; NC_004668.1.
DR   RefSeq; NP_816271.1; NC_004668.1.
DR   RefSeq; NP_816710.1; NC_004668.1.
DR   RefSeq; NP_816817.1; NC_004668.1.
DR   RefSeq; NP_816982.1; NC_004669.1.
DR   RefSeq; NP_816985.1; NC_004669.1.
DR   RefSeq; NP_817006.1; NC_004670.1.
DR   RefSeq; NP_817070.1; NC_004671.1.
DR   RefSeq; WP_000195429.1; NZ_KE136532.1.
DR   AlphaFoldDB; P59787; -.
DR   SMR; P59787; -.
DR   STRING; 226185.EF_0125; -.
DR   DNASU; 1202229; -.
DR   EnsemblBacteria; AAO80000; AAO80000; EF_0125.
DR   EnsemblBacteria; AAO80376; AAO80376; EF_0529.
DR   EnsemblBacteria; AAO81919; AAO81919; EF_2187.
DR   EnsemblBacteria; AAO82341; AAO82341; EF_2632.
DR   EnsemblBacteria; AAO82780; AAO82780; EF_3100.
DR   EnsemblBacteria; AAO82887; AAO82887; EF_3215.
DR   EnsemblBacteria; AAO83053; AAO83053; EF_A0059.
DR   EnsemblBacteria; AAO83056; AAO83056; EF_A0062.
DR   EnsemblBacteria; AAO83077; AAO83077; EF_C0004.
DR   EnsemblBacteria; AAO83141; AAO83141; EF_B0052.
DR   GeneID; 58110055; -.
DR   GeneID; 67496063; -.
DR   KEGG; efa:EF0125; -.
DR   KEGG; efa:EF0529; -.
DR   KEGG; efa:EF2187; -.
DR   KEGG; efa:EF2632; -.
DR   KEGG; efa:EF3100; -.
DR   KEGG; efa:EF3215; -.
DR   KEGG; efa:EF_B0052; -.
DR   KEGG; efa:EF_C0004; -.
DR   KEGG; efa:EFA0059; -.
DR   KEGG; efa:EFA0062; -.
DR   eggNOG; COG3328; Bacteria.
DR   HOGENOM; CLU_036805_8_0_9; -.
DR   OMA; NGQFSTE; -.
DR   Proteomes; UP000001415; Chromosome.
DR   Proteomes; UP000001415; Plasmid pTEF1.
DR   Proteomes; UP000001415; Plasmid pTEF2.
DR   Proteomes; UP000001415; Plasmid pTEF3.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR   InterPro; IPR001207; Transposase_mutator.
DR   PANTHER; PTHR33217; PTHR33217; 1.
DR   Pfam; PF00872; Transposase_mut; 1.
DR   PROSITE; PS01007; TRANSPOSASE_MUTATOR; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Plasmid; Reference proteome;
KW   Transposable element; Transposition.
FT   CHAIN           1..390
FT                   /note="Transposase for insertion sequence element IS256 in
FT                   transposon Tn4001"
FT                   /id="PRO_0000211354"
SQ   SEQUENCE   390 AA;  45674 MW;  28A38C9511BCC512 CRC64;
     MTQVHFTLKS EEIQSIIEYS VKDDVSKNIL TTVFNQLMEN QRTEYIQAKE YERTENRQSQ
     RNGYYERSFT TRVGTLELKV PRTRDGHFSP TVFERYQRNE KALMASMLEM YVSGVSTRKV
     SKIVEELCGK SVSKSFVSSL TEQLEPMVNE WQNRLLSEKN YPYLMTDVLY IKVREENRVL
     SKSCHIAIGI TKDGDREIIG FMIQSGESEE TWTTFFEYLK ERGLQGTELV ISDAHKGLVS
     AIRKSFTNVS WQRCQVHFLR NIFTTIPKKN SKSFREAVKG IFKFTDINLA REAKNRLIHD
     YIDQPKYSKA CASLDDGFED AFQYTVQGNS HNRLKSTNLI ERLNQEVRRR EKIIRIFPNQ
     TSANRLIGAV LMDLHDEWIY SSRKYINFDK