TRA9_MYCTA
ID TRA9_MYCTA Reviewed; 278 AA.
AC A5TY79; O08154; O08156; O08159; O33355; P19774; P75029; P97137; Q9R378;
DT 02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 2.
DT 25-MAY-2022, entry version 60.
DE RecName: Full=Putative transposase for insertion sequence element IS986/IS6110;
DE AltName: Full=ORFB;
GN OrderedLocusNames=MRA_0011;
GN and
GN OrderedLocusNames=MRA_0806;
GN and
GN OrderedLocusNames=MRA_1379;
GN and
GN OrderedLocusNames=MRA_1767;
GN and
GN OrderedLocusNames=MRA_1769;
GN and
GN OrderedLocusNames=MRA_1778;
GN and
GN OrderedLocusNames=MRA_2121;
GN and
GN OrderedLocusNames=MRA_2182;
GN and
GN OrderedLocusNames=MRA_2298;
GN and
GN OrderedLocusNames=MRA_2379;
GN and
GN OrderedLocusNames=MRA_2504;
GN and
GN OrderedLocusNames=MRA_2838;
GN and
GN OrderedLocusNames=MRA_3219;
GN and
GN OrderedLocusNames=MRA_3368;
GN and
GN OrderedLocusNames=MRA_3420;
GN and
GN OrderedLocusNames=MRA_3515;
OS Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=419947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10531227; DOI=10.1128/iai.67.11.5768-5774.1999;
RA Brosch R., Philipp W., Stavropoulos E., Colston M.J., Cole S.T.,
RA Gordon S.V.;
RT "Genomic analysis reveals variation between Mycobacterium tuberculosis
RT H37Rv and the attenuated M. tuberculosis H37Ra.";
RL Infect. Immun. 67:5768-5774(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25177 / H37Ra;
RX PubMed=18584054; DOI=10.1371/journal.pone.0002375;
RA Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., Shi W., Zhang L.,
RA Wang H., Wang S., Zhao G., Zhang Y.;
RT "Genetic basis of virulence attenuation revealed by comparative genomic
RT analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv.";
RL PLoS ONE 3:E2375-E2375(2008).
CC -!- FUNCTION: Involved in the transposition of the insertion sequence.
CC {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABQ71729.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ72535.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ73121.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ73516.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ73522.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ73531.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ73882.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ73944.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ74062.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ74148.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ74275.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ74617.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ75002.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ75151.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ75204.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=ABQ75300.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAB60067.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAB60074.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAB62397.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AJ242908; CAB62397.1; ALT_INIT; Genomic_DNA.
DR EMBL; AJ242907; CAB60074.1; ALT_INIT; Genomic_DNA.
DR EMBL; AJ242907; CAB60067.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ71729.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ72535.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ73121.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ73516.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ73522.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ73531.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ73882.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ73944.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ74062.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ74148.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ74275.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ74617.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ75002.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ75151.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ75204.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP000611; ABQ75300.1; ALT_INIT; Genomic_DNA.
DR AlphaFoldDB; A5TY79; -.
DR STRING; 419947.MRA_0011; -.
DR EnsemblBacteria; ABQ71729; ABQ71729; MRA_0011.
DR EnsemblBacteria; ABQ72535; ABQ72535; MRA_0806.
DR EnsemblBacteria; ABQ73121; ABQ73121; MRA_1379.
DR EnsemblBacteria; ABQ73516; ABQ73516; MRA_1767.
DR EnsemblBacteria; ABQ73522; ABQ73522; MRA_1769.
DR EnsemblBacteria; ABQ73531; ABQ73531; MRA_1778.
DR EnsemblBacteria; ABQ73882; ABQ73882; MRA_2121.
DR EnsemblBacteria; ABQ73944; ABQ73944; MRA_2182.
DR EnsemblBacteria; ABQ74062; ABQ74062; MRA_2298.
DR EnsemblBacteria; ABQ74148; ABQ74148; MRA_2379.
DR EnsemblBacteria; ABQ74275; ABQ74275; MRA_2504.
DR EnsemblBacteria; ABQ74617; ABQ74617; MRA_2838.
DR EnsemblBacteria; ABQ75002; ABQ75002; MRA_3219.
DR EnsemblBacteria; ABQ75151; ABQ75151; MRA_3368.
DR EnsemblBacteria; ABQ75204; ABQ75204; MRA_3420.
DR EnsemblBacteria; ABQ75300; ABQ75300; MRA_3515.
DR KEGG; mra:MRA_0011; -.
DR KEGG; mra:MRA_0806; -.
DR KEGG; mra:MRA_1379; -.
DR KEGG; mra:MRA_1767; -.
DR KEGG; mra:MRA_1769; -.
DR KEGG; mra:MRA_1778; -.
DR KEGG; mra:MRA_2121; -.
DR KEGG; mra:MRA_2182; -.
DR KEGG; mra:MRA_2298; -.
DR KEGG; mra:MRA_2379; -.
DR KEGG; mra:MRA_2504; -.
DR KEGG; mra:MRA_2838; -.
DR KEGG; mra:MRA_3219; -.
DR KEGG; mra:MRA_3368; -.
DR KEGG; mra:MRA_3420; -.
DR KEGG; mra:MRA_3515; -.
DR eggNOG; COG2801; Bacteria.
DR HOGENOM; CLU_027402_4_0_11; -.
DR Proteomes; UP000001988; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.10; -; 1.
DR InterPro; IPR025948; HTH-like_dom.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR Pfam; PF13276; HTH_21; 1.
DR Pfam; PF00665; rve; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 3: Inferred from homology;
KW DNA recombination; DNA-binding; Transposable element; Transposition.
FT CHAIN 1..278
FT /note="Putative transposase for insertion sequence element
FT IS986/IS6110"
FT /id="PRO_0000305176"
FT DOMAIN 101..268
FT /note="Integrase catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00457"
FT CONFLICT 165
FT /note="G -> S (in Ref. 1; CAB62397/CAB60074)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 278 AA; 31369 MW; E4D33328228D7676 CRC64;
MPIAPSTYYD HINREPSRRE LRDGELKEHI SRVHAANYGV YGARKVWLTL NREGIEVARC
TVERLMTKLG LSGTTRGKAR RTTIADPATA RPADLVQRRF GPPAPNRLWV ADLTYVSTWA
GFAYVAFVTD AYARRILGWR VASTMATSMV LDAIEQAIWT RQQEGVLDLK DVIHHTDRGS
QYTSIRFSER LAEAGIQPSV GAVGSSYDNA LAETINGLYK TELIKPGKPW RSIEDVELAT
ARWVDWFNHR RLYQYCGDVP PVELEAAYYA QRQRPAAG
