ID   TRA9_MYCTO              Reviewed;         278 AA.
AC   P9WKH8; L0TCB7; O08154; O08156; O08159; O33355; P0C5G8; P19774; P75029;
AC   P97137; Q9R378;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 23.
DE   RecName: Full=Putative transposase for insertion sequence element IS986/IS6110;
DE   AltName: Full=ORFB;
GN   OrderedLocusNames=MT1803;
GN   and
GN   OrderedLocusNames=MT2881;
GN   and
GN   OrderedLocusNames=MT0413;
GN   and
GN   OrderedLocusNames=MT3100;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Involved in the transposition of the insertion sequence.
CC       {ECO:0000250}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK44637.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAK46076.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAK47204.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAK47429.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000516; AAK46076.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE000516; AAK47204.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE000516; AAK44637.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE000516; AAK47429.1; ALT_INIT; Genomic_DNA.
DR   PIR; H70567; H70567.
DR   AlphaFoldDB; P9WKH8; -.
DR   EnsemblBacteria; AAK44637; AAK44637; MT0413.
DR   EnsemblBacteria; AAK46076; AAK46076; MT1803.
DR   EnsemblBacteria; AAK47204; AAK47204; MT2881.
DR   EnsemblBacteria; AAK47429; AAK47429; MT3100.
DR   KEGG; mtc:MT0413; -.
DR   KEGG; mtc:MT1803; -.
DR   KEGG; mtc:MT2881; -.
DR   KEGG; mtc:MT3100; -.
DR   HOGENOM; CLU_027402_4_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR025948; HTH-like_dom.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF13276; HTH_21; 1.
DR   Pfam; PF00665; rve; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Transposable element; Transposition.
FT   CHAIN           1..278
FT                   /note="Putative transposase for insertion sequence element
FT                   IS986/IS6110"
FT                   /id="PRO_0000427651"
FT   DOMAIN          101..268
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00457"
FT   VARIANT         165
FT                   /note="S -> G (in MT2881)"
SQ   SEQUENCE   278 AA;  31399 MW;  14DC5E8594561BDB CRC64;
     MPIAPSTYYD HINREPSRRE LRDGELKEHI SRVHAANYGV YGARKVWLTL NREGIEVARC
     TVERLMTKLG LSGTTRGKAR RTTIADPATA RPADLVQRRF GPPAPNRLWV ADLTYVSTWA
     GFAYVAFVTD AYARRILGWR VASTMATSMV LDAIEQAIWT RQQESVLDLK DVIHHTDRGS
     QYTSIRFSER LAEAGIQPSV GAVGSSYDNA LAETINGLYK TELIKPGKPW RSIEDVELAT
     ARWVDWFNHR RLYQYCGDVP PVELEAAYYA QRQRPAAG