TRA9_MYCTU
ID TRA9_MYCTU Reviewed; 278 AA.
AC P9WKH9; L0TCB7; O08154; O08156; O08159; O33355; P0C5G8; P19774; P75029;
AC P97137; Q9R378;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=Putative transposase for insertion sequence element IS986/IS6110;
DE AltName: Full=ORFB;
GN OrderedLocusNames=Rv0796; ORFNames=MTV042.06;
GN and
GN OrderedLocusNames=Rv1369c; ORFNames=MTCY02B12.03c;
GN and
GN OrderedLocusNames=Rv1756c; ORFNames=MTCY28.22c;
GN and
GN OrderedLocusNames=Rv1764; ORFNames=MTCY28.30;
GN and
GN OrderedLocusNames=Rv2106; ORFNames=MTCY261.02;
GN and
GN OrderedLocusNames=Rv2167c; ORFNames=MTCY270.01;
GN and
GN OrderedLocusNames=Rv2279; ORFNames=MTCY339.31c;
GN and
GN OrderedLocusNames=Rv2355; ORFNames=MTCY98.24;
GN and
GN OrderedLocusNames=Rv2479c; ORFNames=MTV008.35c;
GN and
GN OrderedLocusNames=Rv2649; ORFNames=MTCY441.18;
GN and
GN OrderedLocusNames=Rv2814c; ORFNames=MTCY16B7.29;
GN and
GN OrderedLocusNames=Rv3185; ORFNames=MTV014.29;
GN and
GN OrderedLocusNames=Rv3187; ORFNames=MTV014.31;
GN and
GN OrderedLocusNames=Rv3326; ORFNames=MTV016.26;
GN and
GN OrderedLocusNames=Rv3380c; ORFNames=MTV004.38c;
GN and
GN OrderedLocusNames=Rv3475; ORFNames=MTCY13E12.28;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1981088; DOI=10.1111/j.1365-2958.1990.tb02073.x;
RA McAdam R.A., Hermans P.W.M., van Soolingen D., Zainuddin Z.F., Catty D.,
RA van Embden J.D.A., Dale J.W.;
RT "Characterization of a Mycobacterium tuberculosis insertion sequence
RT belonging to the IS3 family.";
RL Mol. Microbiol. 4:1607-1613(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
CC -!- FUNCTION: Involved in the transposition of the insertion sequence.
CC -!- SEQUENCE CAUTION:
CC Sequence=CCP43544.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP44128.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP44522.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP44530.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP44881.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP44944.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP45061.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP45143.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP45273.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP45447.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP45614.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP45996.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP45998.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP46147.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP46201.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CCP46297.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; X52471; CAA36710.1; -; Genomic_DNA.
DR EMBL; AL123456; CCP43544.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP44128.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP44522.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP44530.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP44881.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP44944.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP45061.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP45143.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP45273.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP45447.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP45614.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP45996.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP45998.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP46147.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP46201.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL123456; CCP46297.1; ALT_INIT; Genomic_DNA.
DR PIR; H70567; H70567.
DR AlphaFoldDB; P9WKH9; -.
DR STRING; 83332.Rv0796; -.
DR PaxDb; P9WKH9; -.
DR TubercuList; Rv0796; -.
DR TubercuList; Rv1369c; -.
DR TubercuList; Rv1756c; -.
DR TubercuList; Rv1764; -.
DR TubercuList; Rv2106; -.
DR TubercuList; Rv2167c; -.
DR TubercuList; Rv2279; -.
DR TubercuList; Rv2355; -.
DR TubercuList; Rv2479c; -.
DR TubercuList; Rv2649; -.
DR TubercuList; Rv2814c; -.
DR TubercuList; Rv3185; -.
DR TubercuList; Rv3187; -.
DR TubercuList; Rv3326; -.
DR TubercuList; Rv3380c; -.
DR TubercuList; Rv3475; -.
DR eggNOG; COG2801; Bacteria.
DR OMA; HDVARCT; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.10; -; 1.
DR InterPro; IPR025948; HTH-like_dom.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR Pfam; PF13276; HTH_21; 1.
DR Pfam; PF00665; rve; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW DNA recombination; DNA-binding; Reference proteome; Transposable element;
KW Transposition.
FT CHAIN 1..278
FT /note="Putative transposase for insertion sequence element
FT IS986/IS6110"
FT /id="PRO_0000075446"
FT DOMAIN 101..268
FT /note="Integrase catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00457"
SQ SEQUENCE 278 AA; 31369 MW; E4D33328228D7676 CRC64;
MPIAPSTYYD HINREPSRRE LRDGELKEHI SRVHAANYGV YGARKVWLTL NREGIEVARC
TVERLMTKLG LSGTTRGKAR RTTIADPATA RPADLVQRRF GPPAPNRLWV ADLTYVSTWA
GFAYVAFVTD AYARRILGWR VASTMATSMV LDAIEQAIWT RQQEGVLDLK DVIHHTDRGS
QYTSIRFSER LAEAGIQPSV GAVGSSYDNA LAETINGLYK TELIKPGKPW RSIEDVELAT
ARWVDWFNHR RLYQYCGDVP PVELEAAYYA QRQRPAAG
