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TRAA_AGRFC
ID   TRAA_AGRFC              Reviewed;        1100 AA.
AC   Q44349;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   27-MAR-2002, sequence version 2.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Conjugal transfer protein TraA;
GN   Name=traA; OrderedLocusNames=Atu6127; ORFNames=AGR_pTi_237;
OS   Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS   (strain C58)).
OG   Plasmid pTiC58.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC   Agrobacterium tumefaciens complex.
OX   NCBI_TaxID=176299;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8763953; DOI=10.1128/jb.178.14.4233-4247.1996;
RA   Farrand S.K., Hwang I., Cook D.M.;
RT   "The tra region of the nopaline-type Ti plasmid is a chimera with elements
RT   related to the transfer systems of RSF1010, RP4, and F.";
RL   J. Bacteriol. 178:4233-4247(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11743193; DOI=10.1126/science.1066804;
RA   Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA   Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA   Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA   Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA   Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA   Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA   Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA   Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA   Gordon M.P., Olson M.V., Nester E.W.;
RT   "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT   C58.";
RL   Science 294:2317-2323(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C58 / ATCC 33970;
RX   PubMed=11743194; DOI=10.1126/science.1066803;
RA   Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA   Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA   Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA   Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA   Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT   "Genome sequence of the plant pathogen and biotechnology agent
RT   Agrobacterium tumefaciens C58.";
RL   Science 294:2323-2328(2001).
CC   -!- SIMILARITY: Belongs to the MobA/MobL family. {ECO:0000305}.
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DR   EMBL; AF010180; AAC17212.1; -; Genomic_DNA.
DR   EMBL; AE007871; AAK91091.2; -; Genomic_DNA.
DR   PIR; AE3243; AE3243.
DR   PIR; T03419; T03419.
DR   RefSeq; NP_396650.2; NC_003065.3.
DR   RefSeq; WP_010974791.1; NC_003065.3.
DR   AlphaFoldDB; Q44349; -.
DR   SMR; Q44349; -.
DR   EnsemblBacteria; AAK91091; AAK91091; Atu6127.
DR   KEGG; atu:Atu6127; -.
DR   PATRIC; fig|176299.10.peg.5334; -.
DR   HOGENOM; CLU_006069_1_0_5; -.
DR   OMA; DGMELHY; -.
DR   PhylomeDB; Q44349; -.
DR   BioCyc; AGRO:ATU6127-MON; -.
DR   Proteomes; UP000000813; Plasmid Ti.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR027351; (+)RNA_virus_helicase_core_dom.
DR   InterPro; IPR041533; Bep_BID.
DR   InterPro; IPR005053; MobA_MobL.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014136; TraA_Ti.
DR   Pfam; PF17841; Bep_C_terminal; 1.
DR   Pfam; PF03389; MobA_MobL; 1.
DR   Pfam; PF01443; Viral_helicase1; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR02768; TraA_Ti; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Conjugation; Nucleotide-binding; Plasmid; Reference proteome.
FT   CHAIN           1..1100
FT                   /note="Conjugal transfer protein TraA"
FT                   /id="PRO_0000210853"
FT   BINDING         404..411
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        372
FT                   /note="L -> LL (in Ref. 1; AAC17212)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   1100 AA;  123477 MW;  B85D31DB526B7344 CRC64;
     MAIAHFSASI VSRGDGRSVV LSAAYQHCAK MEYEREARTI DYTRKQGLVH QEFILPADAP
     KWVRALIADC SVAGASEAFW NKVEAFEKRS DAQLARDLTI ALPRELTSEQ NIALVRDFVE
     KHILGKGMVA DWVYHDNPGN PHIHLMTTLR PLTEDGFGAK KVAVIGEDGQ LVRTKSGKIL
     YELWAGSTDD FNVVRDGWFE RLNHHLTLGG IDLKIDGRSY EKQGIDLEPT IHLGVGAKAI
     SRKAEQQGVR PELERIELNE ERRSENTRRI LKNPAIVLDL IMREKSVFDE RDVAKVLHRY
     VDDPAVFQQL MLRIILNPEV LRLQRDTIEF ATGEKVPARY STRAMIRLEA TMARQAMWLS
     DKETHAVSTA VLAATFGRHG RLSEEQKAAI ECIAGPARIA AVVGRAGAGK TTMMKAAREA
     WELAGYRVVG GALAGKASEG LDKEAGIESR TLSSWELRWN RGRDVLDNKT VFVMDEAGMV
     ASKQMAGFVD AVVRAGAKIV LVGDPEQLQP IEAGAAFRAI VDRIGYAELE TIYRQREDWM
     RKASLDLARG NVEKALALYN ANARIVGERL KAEAVERLIA DWNRDYDQTK TTLILAHLRR
     DVRMLNVMAR EKLVERGIVG EGHVFRTADG ERRFHAGDQI VFLKNETLLG VKNGMIGHVV
     EAVPNRIVAV VGDRDHRRHV VVEQRFYSNL DHGYATTIHK SQGATVDRVK VLASLSLDRH
     LTYVAMTRHR EDLQLYYGCR SFAFNGGLAK VLSRKNAKET TLDYERGKLY REALRFAENR
     GLHIMQVART MLRDRLDWTL RQKTKVSDLV HRLRALGERL GLDQSPKTQT MKEAAPMVTG
     IKTFSGSVAD TVGDKLGADP TLKQQWEEVS ARFRYVFADP ETAFRAVNFD TVLADKEAAK
     AVLQKLEAEP ASIGALKGKT GILASKTERE ARRVAEVNVP ALKRDLEQYL RMRETATLRI
     VTEEQALRQR VSIDIPALSP AARVVLERVR DAIDRNDLPA ALGYALSNRE TKLEIDGFNQ
     AVTERFGERT LLSNVAREPS GKLYEKLSDG MRPEQKEQLK QAWPIMRTAQ QLAAHERTVQ
     SLKQAEELRQ TLRQAPVLKQ
 
 
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