TRABD_MOUSE
ID TRABD_MOUSE Reviewed; 376 AA.
AC Q99JY4; Q9CYF1;
DT 03-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=TraB domain-containing protein;
GN Name=Trabd;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Embryo;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Mammary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Heart, Liver, Lung, Pancreas, and Spleen;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; AK017745; BAB30908.1; -; mRNA.
DR EMBL; BC005574; AAH05574.1; -; mRNA.
DR CCDS; CCDS49696.1; -.
DR RefSeq; NP_080761.2; NM_026485.2.
DR RefSeq; XP_006521371.1; XM_006521308.3.
DR AlphaFoldDB; Q99JY4; -.
DR BioGRID; 212576; 1.
DR STRING; 10090.ENSMUSP00000080403; -.
DR iPTMnet; Q99JY4; -.
DR PhosphoSitePlus; Q99JY4; -.
DR SwissPalm; Q99JY4; -.
DR EPD; Q99JY4; -.
DR jPOST; Q99JY4; -.
DR MaxQB; Q99JY4; -.
DR PaxDb; Q99JY4; -.
DR PRIDE; Q99JY4; -.
DR ProteomicsDB; 260733; -.
DR Antibodypedia; 14181; 53 antibodies from 16 providers.
DR Ensembl; ENSMUST00000081702; ENSMUSP00000080403; ENSMUSG00000015363.
DR Ensembl; ENSMUST00000165690; ENSMUSP00000131228; ENSMUSG00000015363.
DR GeneID; 67976; -.
DR KEGG; mmu:67976; -.
DR UCSC; uc007xfc.1; mouse.
DR CTD; 80305; -.
DR MGI; MGI:1915226; Trabd.
DR VEuPathDB; HostDB:ENSMUSG00000015363; -.
DR eggNOG; KOG2860; Eukaryota.
DR GeneTree; ENSGT00390000009067; -.
DR HOGENOM; CLU_034593_0_1_1; -.
DR InParanoid; Q99JY4; -.
DR OMA; WMGRRTV; -.
DR OrthoDB; 876990at2759; -.
DR PhylomeDB; Q99JY4; -.
DR TreeFam; TF314184; -.
DR BioGRID-ORCS; 67976; 0 hits in 71 CRISPR screens.
DR ChiTaRS; Trabd; mouse.
DR PRO; PR:Q99JY4; -.
DR Proteomes; UP000000589; Chromosome 15.
DR RNAct; Q99JY4; protein.
DR Bgee; ENSMUSG00000015363; Expressed in lacrimal gland and 232 other tissues.
DR ExpressionAtlas; Q99JY4; baseline and differential.
DR Genevisible; Q99JY4; MM.
DR CDD; cd14726; TraB_PrgY-like; 1.
DR InterPro; IPR002816; TraB/PrgY/GumN_fam.
DR InterPro; IPR046345; TraB_PrgY-like.
DR PANTHER; PTHR21530; PTHR21530; 1.
DR Pfam; PF01963; TraB_PrgY_gumN; 1.
PE 1: Evidence at protein level;
KW Acetylation; Phosphoprotein; Reference proteome.
FT CHAIN 1..376
FT /note="TraB domain-containing protein"
FT /id="PRO_0000050826"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0000250|UniProtKB:Q9H4I3"
FT MOD_RES 64
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q9H4I3"
FT CONFLICT 273
FT /note="L -> R (in Ref. 1; BAB30908)"
FT /evidence="ECO:0000305"
FT CONFLICT 376
FT /note="R -> PPVGGPCKEETAPGGSALRRVGCSRGAGAARLGMSLGTDASKPPPMG
FT A (in Ref. 1)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 376 AA; 42189 MW; 97075D5CB5F41FF9 CRC64;
MEGEEKPAQE ADVEPVVTAG TSEAVPRVLA GDPQNISDVD AFNLLLEMKL KRRRERPNLP
RTVTQLVAED GSRVYVVGTA HFSDDSKRDV VKTIREVQPD VVVVELCQYR VSMLKMDERT
LLREAKEVSL EKLQQAVRQN GLMSGLMQML LLKVSAHITE QLGMAPGGEF REAFKEASKV
PFCKFHLGDR PIPVTFKRAI AALSFWQKVK LAWGLCFLSD PISKDDVERC KQKDLLEQMM
AEMIGEFPDL HRTIVSERDV YLTYMLRQAA RRLELPRASD AEPRKCVPSV VVGVVGMGHV
PGIEKNWSTD LNIQEIMTVP PPSISGRVSR VAVKAAFFGL LGYSLYWMGR RTLNLVLSLP
AAQFCLQRVS EARPGR