ID   TRAC_ECOLI              Reviewed;         875 AA.
AC   P18004;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Protein TraC;
GN   Name=traC; OrderedLocusNames=ECOK12F084;
OS   Escherichia coli (strain K12).
OG   Plasmid F.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-20.
RC   STRAIN=K12;
RX   PubMed=2265751; DOI=10.1016/0378-1119(90)90354-t;
RA   Schandel K.A., Maneewannakul S., Vonder Haar R.A., Ippen-Ihler K.,
RA   Webster R.E.;
RT   "Nucleotide sequence of the F plasmid gene, traC, and identification of its
RT   product.";
RL   Gene 96:137-140(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7915817; DOI=10.1128/mr.58.2.162-210.1994;
RA   Frost L.S., Ippen-Ihler K., Skurray R.A.;
RT   "Analysis of the sequence and gene products of the transfer region of the F
RT   sex factor.";
RL   Microbiol. Rev. 58:162-210(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / CR63;
RA   Shimizu H., Saitoh Y., Suda Y., Uehara K., Sampei G., Mizobuchi K.;
RT   "Complete nucleotide sequence of the F plasmid: its implications for
RT   organization and diversification of plasmid genomes.";
RL   Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 867-875.
RC   STRAIN=K12;
RX   PubMed=1355084; DOI=10.1128/jb.174.17.5567-5574.1992;
RA   Maneewannakul S., Maneewannakul K., Ippen-Ihler K.;
RT   "Characterization, localization, and sequence of F transfer region
RT   products: the pilus assembly gene product TraW and a new product, TrbI.";
RL   J. Bacteriol. 174:5567-5574(1992).
CC   -!- FUNCTION: Required for the assembly of mature F-pilin subunits into
CC       extended F pili.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein.
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DR   EMBL; M30936; AAA24905.1; -; Genomic_DNA.
DR   EMBL; U01159; AAC44180.1; -; Genomic_DNA.
DR   EMBL; AP001918; BAA97954.1; -; Genomic_DNA.
DR   EMBL; M93106; AAA24687.1; -; Genomic_DNA.
DR   PIR; JQ0813; S27572.
DR   RefSeq; NP_061463.1; NC_002483.1.
DR   RefSeq; WP_001064243.1; NZ_CP014273.1.
DR   AlphaFoldDB; P18004; -.
DR   SMR; P18004; -.
DR   PRIDE; P18004; -.
DR   PATRIC; fig|83333.107.peg.628; -.
DR   PRO; PR:P18004; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR043964; P-loop_TraG.
DR   InterPro; IPR014117; TraC-F-type.
DR   InterPro; IPR025955; TraC/Conjuga_ATPase.
DR   InterPro; IPR045978; TRAC_dom.
DR   Pfam; PF19357; DUF5934; 1.
DR   Pfam; PF19044; P-loop_TraG; 1.
DR   Pfam; PF11130; TraC_F_IV; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02746; TraC-F-type; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Conjugation; Direct protein sequencing;
KW   Membrane; Plasmid.
FT   CHAIN           1..875
FT                   /note="Protein TraC"
FT                   /id="PRO_0000068447"
FT   MUTAGEN         811
FT                   /note="R->C: Allows filamentous phage infection in the
FT                   absence of piliation."
SQ   SEQUENCE   875 AA;  99192 MW;  4770FD74538E33F6 CRC64;
     MNNPLEAVTQ AVNSLVTALK LPDESAKANE VLGEMSFPQF SRLLPYRDYN QESGLFMNDT
     TMGFMLEAIP INGANESIVE ALDHMLRTKL PRGIPLCIHL MSSQLVGDRI EYGLREFSWS
     GEQAERFNAI TRAYYMKAAA TQFPLPEGMN LPLTLRHYRV FISYCSPSKK KSRADILEME
     NLVKIIRASL QGASITTQTV DAQAFIDIVG EMINHNPDSL YPKRRQLDPY SDLNYQCVED
     SFDLKVRADY LTLGLRENGR NSTARILNFH LARNPEIAFL WNMADNYSNL LNPELSISCP
     FILTLTLVVE DQVKTHSEAN LKYMDLEKKS KTSYAKWFPS VEKEAKEWGE LRQRLGSGQS
     SVVSYFLNIT AFCKDNNETA LEVEQDILNS FRKNGFELIS PRFNHMRNFL TCLPFMAGKG
     LFKQLKEAGV VQRAESFNVA NLMPLVADNP LTPAGLLAPT YRNQLAFIDI FFRGMNNTNY
     NMAVCGTSGA GKTGLIQPLI RSVLDSGGFA VVFDMGDGYK SLCENMGGVY LDGETLRFNP
     FANITDIDQS AERVRDQLSV MASPNGNLDE VHEGLLLQAV RASWLAKENR ARIDDVVDFL
     KNASDSEQYA ESPTIRSRLD EMIVLLDQYT ANGTYGQYFN SDEPSLRDDA KMVVLELGGL
     EDRPSLLVAV MFSLIIYIEN RMYRTPRNLK KLNVIDEGWR LLDFKNHKVG EFIEKGYRTA
     RRHTGAYITI TQNIVDFDSD KASSAARAAW GNSSYKIILK QSAKEFAKYN QLYPDQFLPL
     QRDMIGKFGA AKDQWFSSFL LQVENHSSWH RLFVDPLSRA MYSSDGPDFE FVQQKRKEGL
     SIHEAVWQLA WKKSGPEMAS LEAWLEEHEK YRSVA