ID   TRAF4_ECOLX             Reviewed;         177 AA.
AC   Q03450;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Plasmid transfer protein TraF;
DE   Flags: Precursor;
GN   Name=traF;
OS   Escherichia coli.
OG   Plasmid IncP-alpha RP4.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1400217; DOI=10.1128/jb.174.20.6666-6673.1992;
RA   Waters V.L., Strack B., Pansegrau W., Lanka E., Guiney D.G.;
RT   "Mutational analysis of essential IncP alpha plasmid transfer genes traF
RT   and traG and involvement of traF in phage sensitivity.";
RL   J. Bacteriol. 174:6666-6673(1992).
CC   -!- FUNCTION: Required for donor-specific phage sensitivity. May be
CC       involved in pilus assembly.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peptidase S26C family. {ECO:0000305}.
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DR   EMBL; M94366; AAA98335.1; -; Genomic_DNA.
DR   RefSeq; WP_011205816.1; NZ_NJTR01000055.1.
DR   AlphaFoldDB; Q03450; -.
DR   MEROPS; S26.014; -.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR   InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR   InterPro; IPR019533; Peptidase_S26.
DR   InterPro; IPR014139; Peptidase_S26C_TraF.
DR   Pfam; PF10502; Peptidase_S26; 1.
DR   SUPFAM; SSF51306; SSF51306; 1.
DR   TIGRFAMs; TIGR02771; TraF_Ti; 1.
PE   3: Inferred from homology;
KW   Conjugation; Periplasm; Plasmid; Signal.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000255"
FT   CHAIN           31..177
FT                   /note="Plasmid transfer protein TraF"
FT                   /id="PRO_0000024515"
SQ   SEQUENCE   177 AA;  18902 MW;  C905111810397334 CRC64;
     MSRFQRLTKY VAIGGGAALL LAGAAYLAGA KVNTTKSIPV GLYWKSNAPV EKGAYVMFCP
     PQVGVFSDAK ERGYIAGGFC PGDYGYMMKR VLAAKGDEVA ITDAGVRVNG GLLPHSALIK
     ADPSGRPLPR YQSDSYTLGT AEVLLMSDVS DTSFDGRYFG PVNRSQIITV IRPVLTW