ID   TRAF5_ECOLX             Reviewed;         178 AA.
AC   Q05119;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Plasmid transfer protein TraF;
DE   Flags: Precursor;
GN   Name=traF;
OS   Escherichia coli.
OG   Plasmid IncP-beta R751.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1400217; DOI=10.1128/jb.174.20.6666-6673.1992;
RA   Waters V.L., Strack B., Pansegrau W., Lanka E., Guiney D.G.;
RT   "Mutational analysis of essential IncP alpha plasmid transfer genes traF
RT   and traG and involvement of traF in phage sensitivity.";
RL   J. Bacteriol. 174:6666-6673(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Thomas C.M.;
RL   Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-8.
RC   STRAIN=ATCC 33694 / HB101;
RX   PubMed=1665997; DOI=10.3109/10425179109020786;
RA   Ziegelin G., Pansegrau W., Strack B., Balzer D., Kroeger M., Kruft V.,
RA   Lanka E.;
RT   "Nucleotide sequence and organization of genes flanking the transfer origin
RT   of promiscuous plasmid RP4.";
RL   DNA Seq. 1:303-327(1991).
CC   -!- FUNCTION: Required for donor-specific phage sensitivity. May be
CC       involved in pilus assembly (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peptidase S26C family. {ECO:0000305}.
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DR   EMBL; M94367; AAA98318.1; -; Genomic_DNA.
DR   EMBL; U67194; AAC64473.1; -; Genomic_DNA.
DR   EMBL; X54458; CAA38326.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q05119; -.
DR   MEROPS; S26.014; -.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR   InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR   InterPro; IPR019533; Peptidase_S26.
DR   InterPro; IPR014139; Peptidase_S26C_TraF.
DR   Pfam; PF10502; Peptidase_S26; 1.
DR   SUPFAM; SSF51306; SSF51306; 1.
DR   TIGRFAMs; TIGR02771; TraF_Ti; 1.
PE   3: Inferred from homology;
KW   Conjugation; Periplasm; Plasmid; Signal.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000255"
FT   CHAIN           31..178
FT                   /note="Plasmid transfer protein TraF"
FT                   /id="PRO_0000024516"
SQ   SEQUENCE   178 AA;  18847 MW;  FF850174B140BB14 CRC64;
     MSRILKRIAA GVVIAGVAAL LLAAGGYAAG ARVNTTKSIP VGLYWTSSAP VEKGAYVLFC
     PPQLGVFDDA KERGYIGAGF CQGGYGYMMK RVLAAKDDAV AVADDGVRVN GELLPLSAPI
     KADKAGRPLP RYQSNSYTLG NSEVLLMSDV SATSFDGRYF GPINRSQIKT VIRPVITW